1-Benzyl-N-(2-nitrocyclohexyl)piperidin-4-amine

Base Information

Chemical Name:1-Benzyl-N-(2-nitrocyclohexyl)piperidin-4-amine
CAS No.:79099-10-8
Molecular Formula:C₁₈H₂₇N₃O₂
Molecular Weight:317.431
Hs Code.:
DSSTox Substance ID:DTXSID10528280

Synonyms:1-Benzyl-N-(2-nitrocyclohexyl)piperidin-4-amine;79099-10-8;SCHEMBL11099318;DTXSID10528280;UQLJRIHTQFMDBQ-UHFFFAOYSA-N;1-Benzyl-4-(2-nitro-cyclohexylamino)-piperidine

Suppliers and Price of 1-Benzyl-N-(2-nitrocyclohexyl)piperidin-4-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 1-Benzyl-N-(2-nitrocyclohexyl)piperidin-4-amine

Chemical Property:

XLogP3:3.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:317.21032711
Heavy Atom Count:23
Complexity:371

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCC(C(C1)NC2CCN(CC2)CC3=CC=CC=C3)[N+](=O)[O-]

Technology Process of 1-Benzyl-N-(2-nitrocyclohexyl)piperidin-4-amine

There total 1 articles about 1-Benzyl-N-(2-nitrocyclohexyl)piperidin-4-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.4%

: 50541-93-0
4-amino-1-benzylpiperidine

: 2562-37-0
1-nitrocyclohexene

: 79099-10-8
1-benzyl-4-(2-nitrocyclohexylamino)piperidine

Guidance literature:: In tetrahydrofuran; for 12h; Ambient temperature;
DOI:10.1248/cpb.31.3186

Reference yield:

: 79099-10-8
1-benzyl-4-(2-nitrocyclohexylamino)piperidine

: 79099-11-9
1-benzyl-4-(2-aminocyclohexylamino)piperidine

Guidance literature:: With hydrogen; nickel; In ethanol; Ambient temperature;
DOI:10.1248/cpb.31.3186

Reference yield:

: 79099-10-8
1-benzyl-4-(2-nitrocyclohexylamino)piperidine

: 79098-63-8
(3aR,7aR)-1-{1-[2-(3,4-Dimethoxy-phenyl)-2-oxo-ethyl]-piperidin-4-yl}-octahydro-benzoimidazol-2-one

Guidance literature:: Multi-step reaction with 4 steps

1: H₂ / Raney-Ni / ethanol / Ambient temperature

2: 43.5 percent / acetonitrile / 12 h / Ambient temperature

3: 77.1 percent / H₂, 0.24N HCl / Pd-C / methanol / 2574.3 Torr

4: Et₃N / methanol / Ambient temperature

With hydrogenchloride; hydrogen; triethylamine; palladium on activated charcoal; nickel; In methanol; ethanol; acetonitrile;
DOI:10.1248/cpb.31.3186