(1S,2R)-2-BROMO-CYCLOPENTANOL

Base Information

• Chemical Name: (1S,2R)-2-BROMO-CYCLOPENTANOL
• CAS No.: 20377-79-1
• Molecular Formula: C₅H₉BrO
• Molecular Weight: 165.03
• Mol file: 20377-79-1.mol

Synonyms:trans-1-hydroxy-2-bromocyclopentane;(+/-)-trans-2-bromocyclopentanol;bromo-2 cyclopentanol trans;trans-2-bromocyclopentanol;(1S,2R)-2-Bromo-cyclopentanol;trans 2-bromocyclopentanol;trans-2-bromocyclopentan-1-ol;

Chemical Property of (1S,2R)-2-BROMO-CYCLOPENTANOL

Chemical Property:

• Vapor Pressure: 0.0593mmHg at 25°C
• Boiling Point: 205.5°Cat760mmHg
• Flash Point: 78.1°C
• PSA: 20.23000
• Density: 1.649g/cm³
• LogP: 1.29470

Purity/Quality:

97% ^*data from raw suppliers

(1S,2R)-2-BROMO-CYCLOPENTANOL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (1S,2R)-2-BROMO-CYCLOPENTANOL

There total 10 articles about (1S,2R)-2-BROMO-CYCLOPENTANOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

Cyclopentene oxide (285-67-6) → (+/-)-trans-2-bromocyclopentanol (28435-62-3,74305-04-7,87014-72-0,122673-88-5,122673-92-1,20377-79-1)

Guidance literature:

With dimethylbromosulphonium bromide; In acetonitrile; at 20 ℃; for 0.333333h;

DOI:10.1016/j.tetlet.2006.04.059

Reference yield: 97.0%

cyclopentene (142-29-0) → (+/-)-trans-2-bromocyclopentanol (28435-62-3,74305-04-7,87014-72-0,122673-88-5,122673-92-1,20377-79-1)

Guidance literature:

With N-Bromosuccinimide; In water;

DOI:10.1016/S0040-4020(01)91179-2

Reference yield: 85.0%

(1S,5R)-6-Oxa-bicyclo[3.1.0]hexane (285-67-6,149827-17-8) → (+/-)-trans-2-bromocyclopentanol (28435-62-3,74305-04-7,87014-72-0,122673-88-5,122673-92-1,20377-79-1)

Guidance literature:

(1S,5R)-6-Oxa-bicyclo[3.1.0]hexane; In dichloromethane; at 0 - 20 ℃;

With water; In dichloromethane; Further stages.;

DOI:10.1071/CH06408

upstream raw materials:

cis 2-bromocyclopentanol

(1R,2S)-2-bromocyclopentyl acetate

2-bromocyclopentanone

cyclopentene

Downstream raw materials:

trans-2-aminocyclopentanol

2-bromocyclopentyl p-toluenesulfonate

(+/-)-trans-2-(N-Benzylamino)cyclopentanol

trans-2-bromo-1-<((4-bromophenyl)sulfonyl)oxy>cyclopentane