Methyl 4'-methoxy-2,3,4,5-tetrahydro[1,1'-biphenyl]-4-carboxylate

Base Information

Chemical Name:Methyl 4'-methoxy-2,3,4,5-tetrahydro[1,1'-biphenyl]-4-carboxylate
CAS No.:79674-03-6
Molecular Formula:C₁₅H₁₈O₃
Molecular Weight:246.306
Hs Code.:
DSSTox Substance ID:DTXSID60508390

Synonyms:79674-03-6;DTXSID60508390;Methyl 4'-methoxy-2,3,4,5-tetrahydro[1,1'-biphenyl]-4-carboxylate

Suppliers and Price of Methyl 4'-methoxy-2,3,4,5-tetrahydro[1,1'-biphenyl]-4-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Methyl 4'-methoxy-2,3,4,5-tetrahydro[1,1'-biphenyl]-4-carboxylate

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:246.125594432
Heavy Atom Count:18
Complexity:314

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=CCC(CC2)C(=O)OC

Technology Process of Methyl 4'-methoxy-2,3,4,5-tetrahydro[1,1'-biphenyl]-4-carboxylate

There total 5 articles about Methyl 4'-methoxy-2,3,4,5-tetrahydro[1,1'-biphenyl]-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: 104306-59-4
2-{Hydroxy-[4-(4-methoxy-phenyl)-cyclohex-3-enyl]-methylene}-malonic acid diethyl ester

: 79674-03-6
4-(4-Methoxy-phenyl)-cyclohex-3-enecarboxylic acid methyl ester

: 104306-60-7
4-p-methoxyphenylbicyclo<2.2.2>octan-2-one

Guidance literature:: In sulfuric acid; water; acetic acid; 1.) 16 h, 10-15 deg C_. 2.) 7 h reflux.;
DOI:10.1016/S0040-4020(01)91364-X

Reference yield:

: 104306-59-4
2-{Hydroxy-[4-(4-methoxy-phenyl)-cyclohex-3-enyl]-methylene}-malonic acid diethyl ester

: 13021-18-6
1-(4'-methoxy-biphenyl-4-yl)-ethanone

: 79674-03-6
4-(4-Methoxy-phenyl)-cyclohex-3-enecarboxylic acid methyl ester

: 104306-60-7
4-p-methoxyphenylbicyclo<2.2.2>octan-2-one

Guidance literature:: With sulfuric acid; water; acetic acid; Product distribution; Mechanism; Concentr_., temp.;
DOI:10.1016/S0040-4020(01)91364-X

Reference yield:

: 49708-14-7
4-(4-methoxy-phenyl)-cyclohex-3-enecarboxylic acid

: 79674-03-6
4-(4-Methoxy-phenyl)-cyclohex-3-enecarboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) NaOMe, MeOH_. 2.) (COCl)2, Py-C₆H_6.

2: diethyl ether / 2 h / -5 - 0 °C

3: acetic acid; H₂SO₄; H₂O / 1.) 16 h, 10-15 deg C_. 2.) 7 h reflux.

In diethyl ether; sulfuric acid; water; acetic acid;
DOI:10.1016/S0040-4020(01)91364-X