Acetic acid, cyano-, 4-nitrophenyl ester

Base Information

• Chemical Name: Acetic acid, cyano-, 4-nitrophenyl ester
• CAS No.: 80256-92-4
• Molecular Formula: C9H6N2O4
• Molecular Weight: 206.158
• Mol file: 80256-92-4.mol

Synonyms:

Chemical Property of Acetic acid, cyano-, 4-nitrophenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Acetic acid, cyano-, 4-nitrophenyl ester

There total 1 articles about Acetic acid, cyano-, 4-nitrophenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) + cyanoacetic acid (372-09-8) → p-nitrophenyl cyanoacetate (80256-92-4)

Guidance literature:

In acetic anhydride; for 1h; Heating;

Reference yield:

p-nitrophenyl cyanoacetate (80256-92-4) → 4-nitro-phenol (100-02-7,78813-13-5,89830-32-0)

Guidance literature:

With potassium chloride; water; In acetonitrile; at 30 ℃; Rate constant; Mechanism;

DOI:10.1039/c39810000884

Reference yield:

p-nitrophenyl cyanoacetate (80256-92-4) → 4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) + cyanoacetic acid (372-09-8)

Guidance literature:

With pH = 7.0; In water; at 28.7 ℃; under 750.06 Torr; Mechanism; Rate constant; Thermodynamic data; pressure-dependence of rates of elimination; activation parameters for hydrolysis: ΔV(excit.), ΔS(excit.), E_A(excit.); var. reaction conditions (pH, pressure);

DOI:10.1039/P29880000557

upstream raw materials:

4-nitro-phenol

cyanoacetic acid

Downstream raw materials:

4-nitro-phenol

cyanoacetic acid

p-nitrophenyl 2-amino-5-methylfuro<3,2-b>pyridine-3-carboxylate

diethyl N-(3-p-nitrophenoxycarbonyl-5-methylfuro<3,2-b>pyridine-2-amino)methylenemalonate

Refernces

• 1、 Inoue, Masashi,Bruice, Thomas C.. "The Influence of Electron Delocalization on the Rate Constants for Competing BAc2 and E1cb Ester Hydrolyses". . p. 884 - 886. Retrieved 2007/10/02.