2,5-Diethylaniline

Base Information

• Chemical Name: 2,5-Diethylaniline
• CAS No.: 80427-50-5
• Molecular Formula: C10H15N
• Molecular Weight: 149.236
• DSSTox Substance ID: DTXSID30462192
• Nikkaji Number: J141.275B
• Wikidata: Q82286687
• Mol file: 80427-50-5.mol

Synonyms:2,5-diethylaniline;80427-50-5;Benzenamine, 2,5-diethyl-;SCHEMBL394899;DTXSID30462192;CS-0283859;EN300-147465

Chemical Property of 2,5-Diethylaniline

Chemical Property:

• XLogP3: 2.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 149.120449483
• Heavy Atom Count: 11
• Complexity: 111

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC1=CC(=C(C=C1)CC)N

Technology Process of 2,5-Diethylaniline

There total 8 articles about 2,5-Diethylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,4-diethylbenzene (105-05-5) → 1-amino-2,5-diethylbenzene (80427-50-5)

Guidance literature:

Multistep reaction; (i) HNO₃, AcOH, Ac₂O, (ii) H₂, Pd-C, EtOH;

DOI:10.1021/jo01278a015

Reference yield:

1,4-diethyl-2-nitro-benzene (10482-00-5) → 1-amino-2,5-diethylbenzene (80427-50-5)

Guidance literature:

With palladium; Hydrogenation;

DOI:10.1002/ardp.19572901204

Reference yield:

1-(4-ethyl-3-nitrophenyl)ethan-1-one (103203-47-0) → 1-amino-2,5-diethylbenzene (80427-50-5)

Guidance literature:

With palladium; Hydrogenation;

DOI:10.1002/ardp.19572901204

upstream raw materials:

1,4-diethyl-2-nitro-benzene

1-(4-ethyl-3-amino-phenyl)-ethanone

1-(4-ethyl-3-nitrophenyl)ethan-1-one

1,4-diethylbenzene

Downstream raw materials:

2,5-diethyl phenol

acetic acid-(2,5-diethyl-anilide)

2,5-diethyl-hydroquinone

C₂₇H₃₄N₂O₄

Refernces