(R)-2-Amino-pent-4-enoic acid methyl ester

Base Information

• Chemical Name: (R)-2-Amino-pent-4-enoic acid methyl ester
• CAS No.: 81136-73-4
• Molecular Formula: C6H11NO2
• Molecular Weight: 129.159
• DSSTox Substance ID: DTXSID80466069
• Nikkaji Number: J1.061.893B
• Wikidata: Q82292464
• Mol file: 81136-73-4.mol

Synonyms:81136-73-4;(R)-2-Amino-pent-4-enoic acid methyl ester;methyl (R)-2-aminopent-4-enoate;METHYL (2R)-2-AMINOPENT-4-ENOATE;4-Pentenoic acid, 2-amino-, methyl ester, (2R)-;SCHEMBL4573274;DTXSID80466069;JHQZRHILTYGZQL-RXMQYKEDSA-N;(R)-Methyl 2-aminopent-4-enoate;AKOS006337823;CS-0455877;EN300-6509099

Chemical Property of (R)-2-Amino-pent-4-enoic acid methyl ester

Chemical Property:

• XLogP3: 0.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 129.078978594
• Heavy Atom Count: 9
• Complexity: 112

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC(=O)C(CC=C)N
• Isomeric SMILES: COC(=O)[C@@H](CC=C)N

Technology Process of (R)-2-Amino-pent-4-enoic acid methyl ester

There total 23 articles about (R)-2-Amino-pent-4-enoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

methanol (67-56-1) + D-allylglycine (54594-06-8) → (R)-2-allylglycine methyl ester (81136-73-4)

Guidance literature:

With hydrogenchloride; at 70 ℃;

Reference yield: 98.0%

methanol (67-56-1) + L-allylglycine (16338-48-0) → methyl (S)-allylglycinate (50299-15-5,70837-19-3,81136-73-4,105929-46-2)

Guidance literature:

With chloro-trimethyl-silane; at 0 - 20 ℃; for 24h;

Reference yield: 95.0%

methanol (67-56-1) + rac-allylglycine (1069-48-3,7685-44-1) → allylglycine methyl ester (50299-15-5,70837-19-3,81136-73-4,105929-46-2)

Guidance literature:

methanol; rac-allylglycine; With thionyl chloride;

With triethylamine; Further stages.;

DOI:10.1016/j.tetlet.2003.10.147

upstream raw materials:

Methyl 2-<(allyloxycarbonyl)amino>-2-methoxyacetate

Methyl 2-(benzhydrylideneamino)-4-pentenoate

methanol

rac-allylglycine

Downstream raw materials:

rac-allylglycine

methyl 2-[(tert-butoxycarbonyl)amino]pent-4-enoate

2-(Toluene-4-sulfonylamino)pent-4-enoic acid methyl ester

N-(2,4-dimethoxybenzyl)-allylglycine methyl ester