Benzaldehyde, 2,3,4-trimethoxy-6-[[(4-methoxyphenyl)methyl]thio]-

Base Information

Chemical Name:Benzaldehyde, 2,3,4-trimethoxy-6-[[(4-methoxyphenyl)methyl]thio]-
CAS No.:823829-22-7
Molecular Formula:C18H20O5S
Molecular Weight:348.42
Hs Code.:
DSSTox Substance ID:DTXSID30470671
Wikidata:Q82298827

Synonyms:823829-22-7;Benzaldehyde, 2,3,4-trimethoxy-6-[[(4-methoxyphenyl)methyl]thio]-;SCHEMBL13402421;DTXSID30470671;2,3,4-trimethoxy-6-(4-methoxybenzylthio)benzaldehyde

Suppliers and Price of Benzaldehyde, 2,3,4-trimethoxy-6-[[(4-methoxyphenyl)methyl]thio]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of Benzaldehyde, 2,3,4-trimethoxy-6-[[(4-methoxyphenyl)methyl]thio]-

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:8
Exact Mass:348.10314491
Heavy Atom Count:24
Complexity:372

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)CSC2=C(C(=C(C(=C2)OC)OC)OC)C=O

Technology Process of Benzaldehyde, 2,3,4-trimethoxy-6-[[(4-methoxyphenyl)methyl]thio]-

There total 7 articles about Benzaldehyde, 2,3,4-trimethoxy-6-[[(4-methoxyphenyl)methyl]thio]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 312300-10-0
(4-methoxybenzyl)(3,4,5-trimethoxyphenyl)sulfane

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 823829-22-7
2,3,4-trimethoxy-6-(4-methoxy-benzylsulfanyl)-benzaldehyde

Guidance literature:: With trichlorophosphate; In dichloromethane; at 150 ℃; for 5h;
DOI:10.1021/ol048145o

Reference yield: 48.0%

: 52978-83-3
2,3,4-trimethoxy-6-nitrobenzaldehyde

: 6258-60-2
p-methoxybenzylmercaptan

: 823829-22-7
2,3,4-trimethoxy-6-(4-methoxy-benzylsulfanyl)-benzaldehyde

Guidance literature:: With potassium hydroxide; In N,N-dimethyl-formamide; at 80 ℃; for 6h;
DOI:10.1039/d0cc07404g

Reference yield:

: 642-71-7
3,4,5-trimethoxyphenol

: 823829-22-7
2,3,4-trimethoxy-6-(4-methoxy-benzylsulfanyl)-benzaldehyde

Guidance literature:: Multi-step reaction with 3 steps

1: aq. K₃PO₄ / toluene / 0 - 20 °C

2: 85 percent / Pd(OAc)2; (R)-(+)-BINAP; Et₃N / dimethylformamide / 0.33 h / 150 °C / microwave irradiation

3: 89 percent / POCl₃ / CH₂Cl₂ / 5 h / 150 °C

With palladium diacetate; potassium phosphate; (R)-2,2'-bis(diphenylphosphanyl)-1,1'-binaphthyl; triethylamine; trichlorophosphate; In dichloromethane; N,N-dimethyl-formamide; toluene; 3: Vilsmeyer formylation;
DOI:10.1021/ol048145o