Technology Process of Carbamic acid, [(1S,2S)-2-(1-piperidinyl)cyclohexyl]-, phenylmethyl
ester
There total 4 articles about Carbamic acid, [(1S,2S)-2-(1-piperidinyl)cyclohexyl]-, phenylmethyl
ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
(+/-)-trans-2-(piperidin-1-yl)cyclohexanamine; ethyl acetate;
With
Candida antarctica lipase B;
at 28 ℃;
for 8h;
benzyl chloroformate;
at 0 ℃;
for 15h;
DOI:10.1002/chem.200400607
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: ethanol / 18 h / Heating
2.1: MsCl; Et3N / diethyl ether / 0 - 20 °C
2.2: aq. NH3 / diethyl ether / 16 h / 20 °C
3.1: Candida antarctica lipase B / 8 h / 28 °C
3.2: 45 percent / 15 h / 0 °C
With
Candida antarctica lipase B; methanesulfonyl chloride; triethylamine;
In
diethyl ether; ethanol;
DOI:10.1002/chem.200400607
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: ethanol / 18 h / Heating
2.1: MsCl; Et3N / diethyl ether / 0 - 20 °C
2.2: aq. NH3 / diethyl ether / 16 h / 20 °C
3.1: Candida antarctica lipase B / 8 h / 28 °C
3.2: 45 percent / 15 h / 0 °C
With
Candida antarctica lipase B; methanesulfonyl chloride; triethylamine;
In
diethyl ether; ethanol;
DOI:10.1002/chem.200400607
