4-(MorpholinoMethyl)benzene-1,2-diaMine

Base Information

Chemical Name:4-(MorpholinoMethyl)benzene-1,2-diaMine
CAS No.:825619-02-1
Molecular Formula:C11H17N3O
Molecular Weight:207.275
Hs Code.:2934999090
Mol file:825619-02-1.mol

Synonyms:4-(morpholin-4-ylmethyl)benzene-1,2-diamine;

Suppliers and Price of 4-(MorpholinoMethyl)benzene-1,2-diaMine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(Morpholinomethyl)benzene-1,2-diamine
100mg
$ 240.00

SynQuest Laboratories
4-(Morpholinomethyl)benzene-1,2-diamine
1 g
$ 848.00

Matrix Scientific
4-(Morpholinomethyl)benzene-1,2-diamine 95%
10g
$ 4008.00

Matrix Scientific
4-(Morpholinomethyl)benzene-1,2-diamine 95%
5g
$ 2402.00

Crysdot
4-(Morpholinomethyl)benzene-1,2-diamine 97%
1g
$ 448.00

Chemenu
4-(Morpholinomethyl)benzene-1,2-diamine 95+%
1g
$ 419.00

Alichem
4-(Morpholinomethyl)benzene-1,2-diamine
250mg
$ 157.70

Alichem
4-(Morpholinomethyl)benzene-1,2-diamine
1g
$ 394.57

AK Scientific
4-(Morpholinomethyl)benzene-1,2-diamine
250mg
$ 343.00

Total 16 raw suppliers

Chemical Property of 4-(MorpholinoMethyl)benzene-1,2-diaMine

Chemical Property:

Boiling Point:372.3±37.0 °C(Predicted)
PKA:7.42±0.10(Predicted)
PSA：64.51000
Density:1.209±0.06 g/cm3(Predicted)
LogP:1.78350
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C

Purity/Quality:

97% ^*data from raw suppliers

4-(Morpholinomethyl)benzene-1,2-diamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-(MorpholinoMethyl)benzene-1,2-diaMine

There total 5 articles about 4-(MorpholinoMethyl)benzene-1,2-diaMine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.6%

: 825619-03-2
4-(3,4-dinitrobenzyl)-morpholine

: 825619-02-1
4-morpholin-4-ylmethylbenzene-1,2-diamine

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In ethanol; ethyl acetate;

Reference yield:

: 528-45-0
3,4-dinitrobenzoic acid

: 825619-02-1
4-morpholin-4-ylmethylbenzene-1,2-diamine

Guidance literature:: Multi-step reaction with 4 steps

1.1: thionyl chloride; N,N-dimethyl-formamide / tetrahydrofuran / 6 h / Reflux

2.1: triethylamine / tetrahydrofuran / 2 h / 0 - 5 °C

2.2: 10 - 20 °C

3.1: sodium tetrahydroborate; boron trifluoride diethyl etherate / tetrahydrofuran / 0 - 20 °C / Inert atmosphere

3.2: 0 °C / Reflux

4.1: 5%-palladium/activated carbon; hydrogen / ethanol / 48 h / 20 °C

With sodium tetrahydroborate; thionyl chloride; 5%-palladium/activated carbon; boron trifluoride diethyl etherate; hydrogen; triethylamine; N,N-dimethyl-formamide; In tetrahydrofuran; ethanol;
DOI:10.1016/j.bmcl.2013.04.039

Reference yield:

: 65003-28-3
(3,4-dinitrophenyl)(morpholin-4-yl)methanone

: 825619-02-1
4-morpholin-4-ylmethylbenzene-1,2-diamine

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium tetrahydroborate; boron trifluoride diethyl etherate / tetrahydrofuran / 0 - 20 °C / Inert atmosphere

1.2: 0 °C / Reflux

2.1: 5%-palladium/activated carbon; hydrogen / ethanol / 48 h / 20 °C

With sodium tetrahydroborate; 5%-palladium/activated carbon; boron trifluoride diethyl etherate; hydrogen; In tetrahydrofuran; ethanol;
DOI:10.1016/j.bmcl.2013.04.039