1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, tris(1,1-diMethylethyl) ethyl ester

Base Information Edit

Chemical Name:1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, tris(1,1-diMethylethyl) ethyl ester
CAS No.:825625-07-8
Molecular Formula:C₃₀H₅₆N₄O₈
Molecular Weight:600.797
Hs Code.:
Mol file:825625-07-8.mol

Synonyms:1-(ethyl acetate)-4,7,10-tris(tert-butoxycarbonylmethyl)-1,4,7,10-tetraazacyclododecane;1-(ethylacetate)-4,7,10-tris(tert-butoxycarbonylmethyl)-1,4,7,10-tetraazacyclododecane;ethyl 4,7,10-tris(tert-butoxycarbonylmethyl)-1,4,7,10-tetraazacyclododecan-1-ylacetate;1,4,7,10-tetraazacyclododecane-1-acetic acid ethyl ester-4,7,10-tris(acetic acid tert-butyl ester);1,4,7-tris(tert-butoxycarbonylmethyl)-10-((ethoxycarbonyl)methyl)-1,4,7,10-tetraazacyclododecane;

Suppliers and Price of 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, tris(1,1-diMethylethyl) ethyl ester

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, tris(1,1-diMethylethyl) ethyl ester Edit

Chemical Property:

Melting Point:>140 °C (decomp)
Boiling Point:614.1±55.0 °C(Predicted)
PKA:5.54±0.20(Predicted)
PSA：118.16000
Density:1.049±0.06 g/cm3(Predicted)
LogP:1.54780

Purity/Quality:: 95%+ ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

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Technology Process of 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, tris(1,1-diMethylethyl) ethyl ester

There total 5 articles about 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, tris(1,1-diMethylethyl) ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 105-36-2
ethyl bromoacetate

: 122555-91-3
1,4,7-tris-tert-butoxycarbonylmethyl-1,4,7,10-tetraazacyclododecane

: 825625-07-8
tri-tert-butyl 2,2’,2’‘-(10-(2-ethoxy-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetate

Guidance literature:: With potassium carbonate; In acetonitrile; at 70 ℃; for 12h;
DOI:10.1021/ja066199i

Reference yield: 99.0%

: 105-36-2
ethyl bromoacetate

: tris(tert-butyl) 2,2',2''-(1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetate hydrobromide

: 825625-07-8
tri-tert-butyl 2,2’,2’‘-(10-(2-ethoxy-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetate

Guidance literature:: tris(tert-butyl) 2,2',2''-(1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetate hydrobromide; With potassium carbonate; In acetonitrile; for 0.5h; Reflux;

ethyl bromoacetate; In acetonitrile; for 48h; Reflux; Inert atmosphere;
DOI:10.1021/ja803520q