3-Pyridinecarboxamide, 2-chloro-N-methyl-N-(2-nitrophenyl)-

Base Information

Chemical Name:3-Pyridinecarboxamide, 2-chloro-N-methyl-N-(2-nitrophenyl)-
CAS No.:826991-85-9
Molecular Formula:C13H10ClN3O3
Molecular Weight:291.694
Hs Code.:
DSSTox Substance ID:DTXSID90479549
Wikidata:Q82313649

Synonyms:826991-85-9;3-Pyridinecarboxamide, 2-chloro-N-methyl-N-(2-nitrophenyl)-;DTXSID90479549

Suppliers and Price of 3-Pyridinecarboxamide, 2-chloro-N-methyl-N-(2-nitrophenyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 3-Pyridinecarboxamide, 2-chloro-N-methyl-N-(2-nitrophenyl)-

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:291.0410689
Heavy Atom Count:20
Complexity:374

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C1=CC=CC=C1[N+](=O)[O-])C(=O)C2=C(N=CC=C2)Cl

Technology Process of 3-Pyridinecarboxamide, 2-chloro-N-methyl-N-(2-nitrophenyl)-

There total 1 articles about 3-Pyridinecarboxamide, 2-chloro-N-methyl-N-(2-nitrophenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 77-78-1
dimethyl sulfate

: 826991-59-7
N-(4-chloro-2-iodo-phenyl)-2-nitro-benzamide

: 826991-85-9
2-chloro-N-methyl-N-(2-nitro-phenyl)-pyridine-3-carboxamide

Guidance literature:: With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; potassium carbonate; In benzene; at 70 - 80 ℃; for 12h;
DOI:10.1016/j.tet.2004.10.061

Reference yield: 92.0%

: 826991-85-9
2-chloro-N-methyl-N-(2-nitro-phenyl)-pyridine-3-carboxamide

: 826991-86-0
N-(2-amino-phenyl)-2-chloro-N-methyl-pyridine-3-carboxamide

Guidance literature:: With iron; acetic acid; In ethanol; for 5h; Heating;
DOI:10.1016/j.tet.2004.10.061

Reference yield:

: 826991-85-9
2-chloro-N-methyl-N-(2-nitro-phenyl)-pyridine-3-carboxamide

: 16287-28-8
6-methyl-6,11-dihydro-5H-pyrido[2,3-b][1,5]benzodiazepin-5-one

Guidance literature:: Multi-step reaction with 2 steps

1: 92 percent / AcOH; Fe dust / ethanol / 5 h / Heating

2: 42 percent / t-BuOK; BINAP / Pd(OAc)2 / toluene / 48 h / Heating

With potassium tert-butylate; iron; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; acetic acid; palladium diacetate; In ethanol; toluene; 2: Buchwald-Hartwig amination;
DOI:10.1016/j.tet.2004.10.061