3-Methyl-2-nitro-1-(2,3-epoxypropoxy)benzene

Base Information

Chemical Name:3-Methyl-2-nitro-1-(2,3-epoxypropoxy)benzene
CAS No.:67823-49-8
Molecular Formula:C10H11NO4
Molecular Weight:209.1986
Hs Code.:
DSSTox Substance ID:DTXSID90987159
Mol file:67823-49-8.mol

Synonyms:3-methyl-2-nitro-1-(2,3-epoxypropoxy)benzene;MNEPB

Suppliers and Price of 3-Methyl-2-nitro-1-(2,3-epoxypropoxy)benzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
3-METHYL-2-NITRO-1-(2,3-EPOXYPROPOXY)BENZENE 95.00%
5MG
$ 500.95

Total 2 raw suppliers

Chemical Property of 3-Methyl-2-nitro-1-(2,3-epoxypropoxy)benzene

Chemical Property:

Vapor Pressure:7.54E-05mmHg at 25°C
Boiling Point:353°Cat760mmHg
Flash Point:168.7°C
PSA：67.58000
Density:1.292g/cm³
LogP:2.20400
XLogP3:1.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:209.06880783
Heavy Atom Count:15
Complexity:240

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

3-METHYL-2-NITRO-1-(2,3-EPOXYPROPOXY)BENZENE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C(=CC=C1)OCC2CO2)[N+](=O)[O-]

Technology Process of 3-Methyl-2-nitro-1-(2,3-epoxypropoxy)benzene

There total 1 articles about 3-Methyl-2-nitro-1-(2,3-epoxypropoxy)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4920-77-8
3-methyl-2-nitrophenol

: 3132-64-7,82584-73-4
1,2-Epoxy-3-bromopropane

: 67823-49-8
2-(3-Methyl-2-nitro-phenoxymethyl)-oxirane

Guidance literature:: With potassium carbonate; In tetrahydrofuran; N,N-dimethyl-formamide; for 2h; Ambient temperature;
DOI:10.1021/jm00063a014

Reference yield: 78.6%

: 67823-49-8
2-(3-Methyl-2-nitro-phenoxymethyl)-oxirane

: 114872-19-4
6-[4-(2-amino-2-methylpropylamino)phenyl]-5-methyl-4,5-dihydro-3(2H)-pyridazinone

: 6-(4-{2-[2-Hydroxy-3-(3-methyl-2-nitro-phenoxy)-propylamino]-2-methyl-propylamino}-phenyl)-5-methyl-4,5-dihydro-2H-pyridazin-3-one

Guidance literature:: In tert-butyl alcohol; at 65 - 70 ℃; for 24h;
DOI:10.1248/cpb.44.2061

Reference yield:

: 67823-49-8
2-(3-Methyl-2-nitro-phenoxymethyl)-oxirane

: 148726-69-6
2-<2-hydroxy-3-(5-methyl-4-phenyl-1H-imidazol-1-yl)propoxy>-6-methylaniline

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NaH / 1.) DMF, 60 deg C, 1 h, 2.) DMF, 60 deg C, 2 h

2: H₂ / 10percent Pd/C / ethyl acetate

With hydrogen; sodium hydride; palladium on activated charcoal; In ethyl acetate;
DOI:10.1021/jm00063a014