4-Fluoro-7-methyl-indan-1-one

Base Information

Chemical Name:4-Fluoro-7-methyl-indan-1-one
CAS No.:828267-45-4
Molecular Formula:C₁₀H₉FO
Molecular Weight:164.179
Hs Code.:
DSSTox Substance ID:DTXSID80464666
Wikidata:Q82290085
Mol file:828267-45-4.mol

Synonyms:828267-45-4;4-Fluoro-7-methyl-indan-1-one;4-Fluoro-7-methyl-2,3-dihydro-1H-inden-1-one;4-fluoro-7-methyl-2,3-dihydroinden-1-one;4-fluoro-7-methylindan-1-one;SCHEMBL14430311;DTXSID80464666;AM9464;MFCD09029800;AKOS006290575;N11082

Suppliers and Price of 4-Fluoro-7-methyl-indan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
4-Fluoro-7-methyl-2,3-dihydro-1H-inden-1-one 95+%
1g
$ 288.00

American Custom Chemicals Corporation
4-FLUORO-7-METHYL-INDAN-1-ONE 95.00%
5MG
$ 496.82

Alichem
4-Fluoro-7-methyl-2,3-dihydro-1H-inden-1-one
1g
$ 313.92

Total 12 raw suppliers

Chemical Property of 4-Fluoro-7-methyl-indan-1-one

Chemical Property:

PSA：17.07000
LogP:2.26300
Storage Temp.:2-8°C
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:164.063743068
Heavy Atom Count:12
Complexity:202

Purity/Quality:

99%, ^*data from raw suppliers

4-Fluoro-7-methyl-2,3-dihydro-1H-inden-1-one 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C2C(=C(C=C1)F)CCC2=O

Technology Process of 4-Fluoro-7-methyl-indan-1-one

There total 3 articles about 4-Fluoro-7-methyl-indan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 33184-16-6
5-fluoro-2-methylbenzoic acid

: 108-59-8
malonic acid dimethyl ester

: 828267-45-4
4-fluoro-7-methyl-1-indanone

Guidance literature:: With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; sodium acetate; at 150 ℃; for 18h; regioselective reaction; Inert atmosphere; Schlenk technique;
DOI:10.1021/acs.orglett.0c02986

Reference yield: 34.0%

: 2-chloro-4-fluoro-1-methyl-3-vinylbenzene

: 828267-45-4
4-fluoro-7-methyl-1-indanone

Guidance literature:: With pyridine; tetrabutyl-ammonium chloride; tri tert-butylphosphoniumtetrafluoroborate; trans-di(μ-acetato)bis[o-(di-o-tolylphosphino)benzyl]dipalladium(II); In 1,4-dioxane; at 170 ℃; for 0.5h; microwave irradiation;
DOI:10.1021/jo048375g