1-Bromo-2-ethenyl-4-fluorobenzene

Base Information

Chemical Name:1-Bromo-2-ethenyl-4-fluorobenzene
CAS No.:828267-47-6
Molecular Formula:C₈H₆BrF
Molecular Weight:201.038
Hs Code.:2903998090
European Community (EC) Number:836-155-3
DSSTox Substance ID:DTXSID80459779
Nikkaji Number:J3.629.373J
Wikidata:Q82283626
Mol file:828267-47-6.mol

Synonyms:828267-47-6;1-bromo-4-fluoro-2-vinylbenzene;1-Bromo-2-ethenyl-4-fluorobenzene;2-Bromo-5-fluorostyrene;Benzene, 1-bromo-2-ethenyl-4-fluoro-;SCHEMBL3744580;DTXSID80459779;CGBWASPURDORDZ-UHFFFAOYSA-N;1-Bromo-4-fluoro-2-vinyl-benzene;MFCD09749661;AKOS022171806;AT35503;PS-11890;CS-0455929;FT-0705415;EN300-705444;4-Bromo-3-vinylfluorobenzene, stabilized with 0.01% 4-t-butylcatechol

Suppliers and Price of 1-Bromo-2-ethenyl-4-fluorobenzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-Bromo-2-ethenyl-4-fluorobenzene
10mg
$ 45.00

TRC
1-Bromo-2-ethenyl-4-fluorobenzene
100mg
$ 130.00

SynQuest Laboratories
2-Bromo-5-fluorostyrene
1 g
$ 269.00

SynQuest Laboratories
2-Bromo-5-fluorostyrene
250 mg
$ 109.00

Apolloscientific
2-Bromo-5-fluorostyrene
250mg
$ 99.00

Apolloscientific
2-Bromo-5-fluorostyrene
1g
$ 244.00

American Custom Chemicals Corporation
4-BROMO-3-VINYLFLUOROBENZENE 95.00%
250MG
$ 216.30

Total 9 raw suppliers

Chemical Property of 1-Bromo-2-ethenyl-4-fluorobenzene

Chemical Property:

Boiling Point:203.9±20.0 °C(Predicted)
Density:1.480±0.06 g/cm3(Predicted)
XLogP3:3.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:199.96369
Heavy Atom Count:10
Complexity:124

Purity/Quality:

97% ^*data from raw suppliers

1-Bromo-2-ethenyl-4-fluorobenzene ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C=CC1=C(C=CC(=C1)F)Br

Technology Process of 1-Bromo-2-ethenyl-4-fluorobenzene

There total 3 articles about 1-Bromo-2-ethenyl-4-fluorobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.6%

: 2065-66-9
methyl-triphenylphosphonium iodide

: 94569-84-3
2-bromo-5-fluorobenzaldehyde

: 828267-47-6
1-bromo-4-fluoro-2-vinylbenzene

Guidance literature:: methyl-triphenylphosphonium iodide; With n-butyllithium; In tetrahydrofuran; at 0 ℃; for 0.5h;

2-bromo-5-fluorobenzaldehyde; In tetrahydrofuran; at 20 ℃; for 16h;

Reference yield: 54.0%

: 1779-49-3
Methyltriphenylphosphonium bromide

: 94569-84-3
2-bromo-5-fluorobenzaldehyde

: 828267-47-6
1-bromo-4-fluoro-2-vinylbenzene

Guidance literature:: With potassium carbonate; In 1,4-dioxane; at 110 ℃; for 10h; Inert atmosphere;
DOI:10.1021/acs.orglett.1c00898

Reference yield:

: 460-00-4
1-Bromo-4-fluorobenzene

: 828267-47-6
1-bromo-4-fluoro-2-vinylbenzene

Guidance literature:: Multi-step reaction with 2 steps

1.1: lithium diisopropyl amide / tetrahydrofuran / 0.83 h / -84 - 0 °C / Inert atmosphere

1.2: 3 h / Inert atmosphere

2.1: n-butyllithium / tetrahydrofuran / 0.25 h / 0 °C / Inert atmosphere

2.2: 2.25 h

With n-butyllithium; lithium diisopropyl amide; In tetrahydrofuran; 2.1: |Wittig Olefination;
DOI:10.1021/ja306446m