2-(Hydroxyimino)-3-phenylpropionic acid ethyl ester

Base Information

Chemical Name:2-(Hydroxyimino)-3-phenylpropionic acid ethyl ester
CAS No.:6943-96-0
Molecular Formula:C₁₁H₁₃NO₃
Molecular Weight:207.229
Hs Code.:
NSC Number:52873
Nikkaji Number:J1.953.614I

Synonyms:NSC52873;2-(Hydroxyimino)-3-phenylpropionic acid ethyl ester;SCHEMBL6156969;SCHEMBL6156980;NSC-52873;6943-96-0

Suppliers and Price of 2-(Hydroxyimino)-3-phenylpropionic acid ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 2-(Hydroxyimino)-3-phenylpropionic acid ethyl ester

Chemical Property:

Vapor Pressure:1.96E-05mmHg at 25°C
Boiling Point:347.9°Cat760mmHg
Flash Point:164.2°C
Density:1.11g/cm³
XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:207.08954328
Heavy Atom Count:15
Complexity:232

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(=NO)CC1=CC=CC=C1
Isomeric SMILES:CCOC(=O)/C(=N/O)/CC1=CC=CC=C1

Technology Process of 2-(Hydroxyimino)-3-phenylpropionic acid ethyl ester

There total 7 articles about 2-(Hydroxyimino)-3-phenylpropionic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.5%

: 607-81-8
diethyl 2-benzylmalonate

: 6943-96-0,70564-52-2,70564-53-3
ethyl 2-(hydroxyimino)-3-phenylpropanoate

Guidance literature:: With sulfuric acid; potassium carbonate; sodium nitrite; In ethanol; water; at 10 ℃; for 5h; Temperature;
DOI:10.1039/c5ra21597h

Reference yield: 75.0%

: 620-79-1
Ethyl 2-benzylacetoacetate

: 6943-96-0,70564-52-2,70564-53-3
ethyl 2-(hydroxyimino)-3-phenylpropanoate

Guidance literature:: With ethyl nitrite; sodium ethanolate; In ethanol; at 0 - 5 ℃; for 2h;
DOI:10.1016/j.bmc.2005.02.024

Reference yield:

: 100-44-7
benzyl chloride

: 6943-96-0,70564-52-2,70564-53-3
ethyl 2-(hydroxyimino)-3-phenylpropanoate

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / ethanol / 8 h / 65 °C

2: ethyl nitrite; sodium ethanolate / ethanol / 12 h / -15 °C / Cooling

With ethyl nitrite; sodium ethanolate; potassium carbonate; In ethanol;
DOI:10.1016/j.bmc.2016.08.038