3-(4-Aminophenyl)-7-iodothieno[3,2-c]pyridin-4-amine

Base Information

Chemical Name:3-(4-Aminophenyl)-7-iodothieno[3,2-c]pyridin-4-amine
CAS No.:832695-09-7
Molecular Formula:C13H10IN3S
Molecular Weight:367.213
Hs Code.:
DSSTox Substance ID:DTXSID90593931
Wikidata:Q82488580

Synonyms:3-(4-aminophenyl)-7-iodothieno[3,2-c]pyridin-4-amine;832695-09-7;starbld0031109;SCHEMBL3377004;DTXSID90593931;COPOUPWFTNTBGO-UHFFFAOYSA-N;DB-127999;3-(4-aminophenyl)-7-iodo-thieno[3,2-c]pyridin-4-amine

Suppliers and Price of 3-(4-Aminophenyl)-7-iodothieno[3,2-c]pyridin-4-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 3-(4-Aminophenyl)-7-iodothieno[3,2-c]pyridin-4-amine

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:366.96402
Heavy Atom Count:18
Complexity:296

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C2=CSC3=C2C(=NC=C3I)N)N

Technology Process of 3-(4-Aminophenyl)-7-iodothieno[3,2-c]pyridin-4-amine

There total 6 articles about 3-(4-Aminophenyl)-7-iodothieno[3,2-c]pyridin-4-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 832695-04-2
t-butyl-4-(4-aminothieno[3,2-c]pyridine-3-yl)phenylcarbamate

: 832695-09-7
3-(4-aminophenyl)-7-iodothieno[3,2-c]pyridin-4-amine

Guidance literature:: Multi-step reaction with 2 steps

1: N-iodosuccinimide / dimethylformamide

2: TFA

With N-iodo-succinimide; trifluoroacetic acid; In N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2006.12.015

Reference yield:

: 799293-85-9
3-bromo-4-amino-[3,2-c]-thienopyridine

: 832695-09-7
3-(4-aminophenyl)-7-iodothieno[3,2-c]pyridin-4-amine

Guidance literature:: Multi-step reaction with 3 steps

1: Na₂CO₃ / Pd(PPh₃)4 / 1,2-dimethoxy-ethane; H₂O / 90 °C

2: N-iodosuccinimide / dimethylformamide

3: TFA

With N-iodo-succinimide; sodium carbonate; trifluoroacetic acid; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,2-dimethoxyethane; water; N,N-dimethyl-formamide; 1: Suzuki coupling;
DOI:10.1016/j.bmcl.2006.12.015

Reference yield:

: 799293-83-7
3-bromo-4-hydroxy-[3,2-c]-thienopyridine

: 832695-09-7
3-(4-aminophenyl)-7-iodothieno[3,2-c]pyridin-4-amine

Guidance literature:: Multi-step reaction with 5 steps

1: POCl₃

2: NH₃ / dioxane / 160 °C / 14997.3 Torr

3: Na₂CO₃ / Pd(PPh₃)4 / 1,2-dimethoxy-ethane; H₂O / 90 °C

4: N-iodosuccinimide / dimethylformamide

5: TFA

With N-iodo-succinimide; ammonia; sodium carbonate; trifluoroacetic acid; trichlorophosphate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; 1,2-dimethoxyethane; water; N,N-dimethyl-formamide; 3: Suzuki coupling;
DOI:10.1016/j.bmcl.2006.12.015