3-Bromothieno[3,2-c]pyridin-4-amine

Base Information

• Chemical Name: 3-Bromothieno[3,2-c]pyridin-4-amine
• CAS No.: 799293-85-9
• Molecular Formula: C7H5BrN2S
• Molecular Weight: 229.1
• Hs Code.: 2934999090
• European Community (EC) Number: 632-871-3
• DSSTox Substance ID: DTXSID70593954
• Wikidata: Q82488612
• Mol file: 799293-85-9.mol

Synonyms:3-bromothieno[3,2-c]pyridin-4-amine;799293-85-9;Thieno[3,2-c]pyridin-4-amine, 3-bromo-;3-BROMO-4-AMINOTHIENO[3,2-C]PYRIDINE;4-AMINO-3-BROMOTHIENO[3,2-C]PYRIDINE;3-bromo-Thieno[3,2-c]pyridin-4-amine;MFCD08275115;SCHEMBL868356;AMY874;DTXSID70593954;NRVPVUKWJYSNTO-UHFFFAOYSA-N;AKOS015919630;CS-W018830;FS-3333;PB32605;4-Amino-3-bromo-thieno[3,2-c]pyridine;DA-23888;SY097772;3-Bromothieno[3 pound not2-c]pyridin-4-amine;3-BROMO-THIENO[3,2-C]PYRIDIN-4-YLAMINE;A864781

Chemical Property of 3-Bromothieno[3,2-c]pyridin-4-amine

Chemical Property:

• Melting Point: 157-160 °C
• Boiling Point: 396.9±37.0 °C(Predicted)
• PKA: 5.59±0.40(Predicted)
• PSA: 67.88000
• Density: 1.836±0.06 g/cm3(Predicted)
• LogP: 2.57110
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• XLogP3: 2.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 227.93568
• Heavy Atom Count: 11
• Complexity: 155

Purity/Quality:

97% ^*data from raw suppliers

3-Bromothieno[3,2-c]pyridin-4-amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CN=C(C2=C1SC=C2Br)N
• Uses: 3-Bromothieno[3,2-c]pyridin-4-amine is used in preparation of organic compounds for organic electroluminescent devices.

Technology Process of 3-Bromothieno[3,2-c]pyridin-4-amine

There total 11 articles about 3-Bromothieno[3,2-c]pyridin-4-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

3-bromo-4-chloro-[3,2-c]-thienopyridine (29064-82-2) → 3-bromo-4-amino-[3,2-c]-thienopyridine (799293-85-9)

Guidance literature:

With ammonium hydroxide; In 1,4-dioxane; at 150 ℃; for 18h;

DOI:10.1016/j.bmcl.2006.12.035

Reference yield:

3-bromothieno[3,2-c]pyridin-4(5H)-one (799293-83-7) → 3-bromo-4-amino-[3,2-c]-thienopyridine (799293-85-9) + 3-bromo-4-chloro-[3,2-c]-thienopyridine (29064-82-2)

Guidance literature:

In trichlorophosphate;

Reference yield:

→ 3-bromofuro[3,2-c]pyridin-4-ylamine (799293-73-5) + 3-bromo-4-amino-[3,2-c]-thienopyridine (799293-85-9)

Guidance literature:

upstream raw materials:

3-bromo-4-chloro-[3,2-c]-thienopyridine

3-bromothieno[3,2-c]pyridin-4(5H)-one

3-bromo-4-hydroxy-[3,2-c]-thienopyridine

trans-3-(4-bromothiophen-2-yl)-acryloyl azide

Downstream raw materials:

3-bromo-7-iodothieno[3,2-c]pyridin-4-amine