4-[2-(Dimethylamino)ethyl]benzonitrile

Base Information

Chemical Name:4-[2-(Dimethylamino)ethyl]benzonitrile
CAS No.:83937-66-0
Molecular Formula:C11H14N2
Molecular Weight:174.246
Hs Code.:
DSSTox Substance ID:DTXSID20543247
Nikkaji Number:J2.711.812G

Synonyms:4-[2-(Dimethylamino)ethyl]benzonitrile;83937-66-0;DTXSID20543247

Suppliers and Price of 4-[2-(Dimethylamino)ethyl]benzonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-[2-(Dimethylamino)ethyl]benzonitrile

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:174.115698455
Heavy Atom Count:13
Complexity:182

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN(C)CCC1=CC=C(C=C1)C#N

Technology Process of 4-[2-(Dimethylamino)ethyl]benzonitrile

There total 5 articles about 4-[2-(Dimethylamino)ethyl]benzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 102101-51-9
(4-Cyano-benzyl)-dimethyl-trimethylsilanylmethyl-ammonium; bromide

: 83937-66-0
2-(4-cyanophenyl)-1-N,N-dimethylaminoethane

: 102101-53-1
3-Dimethylaminomethyl-4-methyl-benzonitrile

Guidance literature:: With cesium fluoride; In N,N,N,N,N,N-hexamethylphosphoric triamide; at 10 ℃; for 5h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; Irradiation;
DOI:10.1021/jo00044a050

Reference yield:

: 102101-51-9
(4-Cyano-benzyl)-dimethyl-trimethylsilanylmethyl-ammonium; bromide

: 83937-66-0
2-(4-cyanophenyl)-1-N,N-dimethylaminoethane

: 4-Dimethylaminomethyl-3-methyl-benzonitrile

Guidance literature:: With cesium fluoride; In N,N,N,N,N,N-hexamethylphosphoric triamide; for 25h; Ambient temperature;
DOI:10.1021/jo00385a035

Reference yield:

: 17201-43-3
4-cyanobenzyl bromide

: 83937-66-0
2-(4-cyanophenyl)-1-N,N-dimethylaminoethane

Guidance literature:: Multi-step reaction with 2 steps

1: acetone

2: 16.8 percent Chromat_. / CsF / hexamethylphosphoric acid triamide / 25 h / Ambient temperature

With cesium fluoride; In N,N,N,N,N,N-hexamethylphosphoric triamide; acetone;
DOI:10.1039/c39850001684