1-benzyl-3-hydroxy-3-(2-oxo-2-phenylethyl)-1,3-dihydro-2H-indol-2-one

Base Information

Chemical Name:1-benzyl-3-hydroxy-3-(2-oxo-2-phenylethyl)-1,3-dihydro-2H-indol-2-one
CAS No.:84003-25-8
Molecular Formula:C23H19NO3
Molecular Weight:357.409
Hs Code.:
Mol file:84003-25-8.mol

Synonyms:1-Benzyl-3-hydroxy-3-(2-oxo-2-phenyl-ethyl)-1,3-dihydro-indol-2-one;1-benzyl-3-hydroxy-3-phenacyloxindole;N-benzyl-3-hydroxy-3-(2-phenyl-2-oxoethyl)-2-oxindole;

Suppliers and Price of 1-benzyl-3-hydroxy-3-(2-oxo-2-phenylethyl)-1,3-dihydro-2H-indol-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-benzyl-3-hydroxy-3-(2-oxo-2-phenylethyl)-1,3-dihydro-2H-indol-2-one

Chemical Property:

Melting Point:170 - 174 °C (ethanol)
PSA：57.61000
LogP:3.75900

Purity/Quality:

Safty Information:

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Technology Process of 1-benzyl-3-hydroxy-3-(2-oxo-2-phenylethyl)-1,3-dihydro-2H-indol-2-one

There total 7 articles about 1-benzyl-3-hydroxy-3-(2-oxo-2-phenylethyl)-1,3-dihydro-2H-indol-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 1217-89-6
1-benzylisatin

: 614-20-0
3-oxo-3-phenylpropionic acid

: 84003-25-8
1-benzyl-3-hydroxy-3-(2-oxo-2-phenylethyl)indolin-2-one

Guidance literature:: In ethyl acetate; at 20 ℃; for 3h; Molecular sieve; Sealed tube;
DOI:10.1016/j.tetlet.2013.06.030

Reference yield: 82.0%

: 28284-05-1
N-benzoylisatin

: 98-86-2
acetophenone

: 84003-25-8
1-benzyl-3-hydroxy-3-(2-oxo-2-phenylethyl)indolin-2-one

Guidance literature:: With diethylamine; In methanol; at 20 ℃;
DOI:10.1016/S0040-4020(02)01048-7

Reference yield: 57.0%

: 7135-32-2
1-benzylindolin-2-one

: 98-86-2
acetophenone

: 84003-25-8
1-benzyl-3-hydroxy-3-(2-oxo-2-phenylethyl)indolin-2-one

Guidance literature:: With tetrabutyl ammonium fluoride; In N,N-dimethyl-formamide; at 20 ℃; for 18h; Molecular sieve;
DOI:10.1002/chem.201504282