Bicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylic acid, 2-Methyl ester

Base Information

• Chemical Name: Bicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylic acid, 2-Methyl ester
• CAS No.: 84328-14-3
• Molecular Formula: C10H10O4
• Molecular Weight: 194.18400
• Hs Code.: 2918990090
• Mol file: 84328-14-3.mol

Synonyms:3-carboxy-1-indanone methyl ester;Methyl 3-oxo-1-indanecarboxylate;Methyl 3-oxo-indan-1-carboxylate;methyl indan-3-one-1-carboxylate;Methyl 3-oxo-2,3-dihydro-1H-indene-1-carboxylate;

Chemical Property of Bicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylic acid, 2-Methyl ester

Chemical Property:

• PSA: 63.60000
• LogP: 0.74650

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

3-(methoxycarbonyl)bicyclo[2.2.1]hepta-2,5-diene-2-carboxylicacid 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Bicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylic acid, 2-Methyl ester

There total 4 articles about Bicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylic acid, 2-Methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

dimethyl bicyclo[2.2.1]hept-2,5-diene-2,3-dicarboxylate (947-57-9) → 2-(methoxycarbonyl)bicyclo[2.2.1]hepta-2,5-diene-3-carboxylic acid (84328-14-3)

Guidance literature:

With sodium hydroxide; In tetrahydrofuran; at 0 ℃;

DOI:10.1021/jo0001986

Reference yield: 73.0%

methanol (67-56-1) + bicyclo<2.2.1>hepta-2,3-dicarboxylic anhydride (17397-31-8) → 2-(methoxycarbonyl)bicyclo[2.2.1]hepta-2,5-diene-3-carboxylic acid (84328-14-3)

Guidance literature:

In acetone; at 0 ℃; for 1h;

DOI:10.1021/jo00355a006

Reference yield:

dimethyl bicyclo[2.2.1]hept-2,5-diene-2,3-dicarboxylate (947-57-9) → bicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylic acid (15872-28-3) + 2-(methoxycarbonyl)bicyclo[2.2.1]hepta-2,5-diene-3-carboxylic acid (84328-14-3)

Guidance literature:

With sodium hydroxide; water; In tetrahydrofuran; at 0 ℃; Product distribution / selectivity;

upstream raw materials:

methanol

bicyclo<2.2.1>hepta-2,3-dicarboxylic anhydride

dimethyl bicyclo[2.2.1]hept-2,5-diene-2,3-dicarboxylate

3-(methoxycarbonyl)quadricyclane-2-carboxylic acid

Downstream raw materials:

bicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylic acid 2-[3,5-bis-(4-benzoyl-benzyloxy)-benzyl] ester 3-methyl ester