Technology Process of 2-Bromo-N-(2-chloro-1-oxo-1lambda~5~-pyridin-3-yl)benzamide
There total 1 articles about 2-Bromo-N-(2-chloro-1-oxo-1lambda~5~-pyridin-3-yl)benzamide which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
dihydrogen peroxide; acetic acid;
at 55 - 60 ℃;
for 24h;
bath temperature;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: conc. NH4OH, CuSO4*5H2O, NaCl / 3 h / 60 °C
2: 96 percent / 5percent aq. HCl / various solvent(s) / 1.5 h / 110 °C / bath temperature
3: acetonitrile / 2 h / 80 °C
4: 95 percent / toluene / 2 h / 80 °C
5: 100 percent / H2 / Raney nickel / bis-(2-methoxy-ethyl) ether / 16 h / 50 °C
With
hydrogenchloride; ammonium hydroxide; hydrogen; copper(II) sulfate; sodium chloride;
nickel;
In
diethylene glycol dimethyl ether; toluene; acetonitrile;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: conc. NH4OH, CuSO4*5H2O, NaCl / 3 h / 60 °C
2: 96 percent / 5percent aq. HCl / various solvent(s) / 1.5 h / 110 °C / bath temperature
3: 65 percent / 50percent aq. KOH / tetrabutylammonium chloride / toluene / 4 h / Heating
With
hydrogenchloride; potassium hydroxide; ammonium hydroxide; copper(II) sulfate; sodium chloride;
tetrabutyl-ammonium chloride;
In
toluene;
