Butyl 7-(benzyloxy)-1H-indole-2-carboxylate

Base Information

Chemical Name:Butyl 7-(benzyloxy)-1H-indole-2-carboxylate
CAS No.:84639-35-0
Molecular Formula:C₂₀H₂₁NO₃
Molecular Weight:323.392
Hs Code.:
DSSTox Substance ID:DTXSID90531393
Wikidata:Q82403223

Synonyms:84639-35-0;BUTYL 7-(BENZYLOXY)-1H-INDOLE-2-CARBOXYLATE;SCHEMBL10509285;DTXSID90531393;KCQNTNVJTVJPGZ-UHFFFAOYSA-N;7-benzyloxyindole-2-carboxylic acid n-butyl ester

Suppliers and Price of Butyl 7-(benzyloxy)-1H-indole-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Butyl 7-(benzyloxy)-1H-indole-2-carboxylate

Chemical Property:

XLogP3:5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:8
Exact Mass:323.15214353
Heavy Atom Count:24
Complexity:394

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCCCOC(=O)C1=CC2=C(N1)C(=CC=C2)OCC3=CC=CC=C3

Technology Process of Butyl 7-(benzyloxy)-1H-indole-2-carboxylate

There total 5 articles about Butyl 7-(benzyloxy)-1H-indole-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 61535-21-5
1-(benzyloxy)-3-methyl-2-nitrobenzene

: 84639-35-0
butyl 7-benzyloxyindole-2-carboxylate

Guidance literature:: Multi-step reaction with 5 steps

1: 100 percent / KOEt / diethyl ether / 20 h / Heating

2: 61 percent / iron powder / acetic acid / 3 h / 80 - 90 °C

3: 95 percent / 2 N NaOH / tetrahydrofuran; methanol / 24 h / Ambient temperature

4: SOCl₂ / toluene / 2 h / 90 °C

5: 1 h / Heating

With sodium hydroxide; thionyl chloride; potassium ethoxide; iron; In tetrahydrofuran; methanol; diethyl ether; acetic acid; toluene;

Reference yield:

: 84639-19-0
7-(benzyloxy)-1-H-indole-2-carboxylic acid

: 84639-35-0
butyl 7-benzyloxyindole-2-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: SOCl₂ / toluene / 2 h / 90 °C

2: 1 h / Heating

With thionyl chloride; In toluene;

Reference yield:

: 84639-06-5
7-benzyloxyindole-2-carboxylic acid ethyl ester

: 84639-35-0
butyl 7-benzyloxyindole-2-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: 95 percent / 2 N NaOH / tetrahydrofuran; methanol / 24 h / Ambient temperature

2: SOCl₂ / toluene / 2 h / 90 °C

3: 1 h / Heating

With sodium hydroxide; thionyl chloride; In tetrahydrofuran; methanol; toluene;