1-Methyl-5-nitro-3-phenyl-1H-indole-2-carbaldehyde

Base Information

Chemical Name:1-Methyl-5-nitro-3-phenyl-1H-indole-2-carbaldehyde
CAS No.:84858-14-0
Molecular Formula:C16H12N2O3
Molecular Weight:280.283
Hs Code.:
DSSTox Substance ID:DTXSID40527625
Wikidata:Q82396843

Synonyms:1-Methyl-5-nitro-3-phenyl-1H-indole-2-carbaldehyde;84858-14-0;1-methyl-2-formyl-3-phenyl-5-nitroindole;DTXSID40527625

Suppliers and Price of 1-Methyl-5-nitro-3-phenyl-1H-indole-2-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 1-Methyl-5-nitro-3-phenyl-1H-indole-2-carbaldehyde

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:280.08479225
Heavy Atom Count:21
Complexity:403

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C2=C(C=C(C=C2)[N+](=O)[O-])C(=C1C=O)C3=CC=CC=C3

Technology Process of 1-Methyl-5-nitro-3-phenyl-1H-indole-2-carbaldehyde

There total 5 articles about 1-Methyl-5-nitro-3-phenyl-1H-indole-2-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 89159-60-4
(1-methyl-5-nitro-3-phenyl-1H-indol-2-yl)methanol

: 84858-14-0
1-methyl-2-formyl-3-phenyl-5-nitroindole

Guidance literature:: With chromium(VI) oxide; In pyridine; at 20 ℃; for 12h;
DOI:10.1007/BF00842836

Reference yield:

: 41018-87-5
2-methyl-3-phenyl-5-nitroindole

: 84858-14-0
1-methyl-2-formyl-3-phenyl-5-nitroindole

Guidance literature:: Multi-step reaction with 4 steps

1: 82 percent / 50percent aq. KOH / acetone / 1 h / 20 °C

2: 95 percent / Br₂ / 1,2-dichloro-ethane / 1 h / Irradiation

3: 73 percent / H₂O / dioxane / 4 h / Heating

4: 70 percent / CrO₃ / pyridine / 12 h / 20 °C

With chromium(VI) oxide; potassium hydroxide; water; bromine; In 1,4-dioxane; pyridine; 1,2-dichloro-ethane; acetone;
DOI:10.1007/BF00842836

Reference yield:

: 68285-93-8
1,2-dimethyl-3-phenyl-5-nitroindole

: 84858-14-0
1-methyl-2-formyl-3-phenyl-5-nitroindole

Guidance literature:: Multi-step reaction with 3 steps

1: 95 percent / Br₂ / 1,2-dichloro-ethane / 1 h / Irradiation

2: 73 percent / H₂O / dioxane / 4 h / Heating

3: 70 percent / CrO₃ / pyridine / 12 h / 20 °C

With chromium(VI) oxide; water; bromine; In 1,4-dioxane; pyridine; 1,2-dichloro-ethane;
DOI:10.1007/BF00842836