2-Bromophenyl dipropan-2-ylphosphinite

Base Information

• Chemical Name: 2-Bromophenyl dipropan-2-ylphosphinite
• CAS No.: 84998-58-3
• Molecular Formula: C12H18BrOP
• Molecular Weight: 289.152
• DSSTox Substance ID: DTXSID90517450
• Nikkaji Number: J2.621.275H
• Wikidata: Q82379478
• Mol file: 84998-58-3.mol

Synonyms:84998-58-3;2-Bromophenyl dipropan-2-ylphosphinite;SCHEMBL4745194;DTXSID90517450

Chemical Property of 2-Bromophenyl dipropan-2-ylphosphinite

Chemical Property:

• XLogP3: 4.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 288.02786
• Heavy Atom Count: 15
• Complexity: 177

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)P(C(C)C)OC1=CC=CC=C1Br

Technology Process of 2-Bromophenyl dipropan-2-ylphosphinite

There total 2 articles about 2-Bromophenyl dipropan-2-ylphosphinite which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

2-hydroxybromobenzene (95-56-7) + Chlorodiisopropylphosphane (40244-90-4) → Diisopropylphosphinigsaeure-o-bromphenylester (84998-58-3)

Guidance literature:

With TEA; In diethyl ether; at 20 ℃; for 24h;

Reference yield: 66.0%

2-hydroxybromobenzene (95-56-7) + N-dimethylaminodiisopropylphosphine (72740-05-7) → Diisopropylphosphinigsaeure-o-bromphenylester (84998-58-3)

Guidance literature:

Heating;

DOI:10.1016/S0022-328X(00)99558-5

Reference yield: 97.0%

dichloro( 1,5-cyclooctadiene)platinum(ll) (12080-32-9) + Diisopropylphosphinigsaeure-o-bromphenylester (84998-58-3) → cis-[PtCl2((2-bromophenoxy)diisopropylphosphane)2] (952685-27-7)

Guidance literature:

In dichloromethane; (Ar), Schlenk techniques; ligand and Pt compd. (2:1), stirred overnight at room temp.; evapd., washed (Et2O), dried (vac.); elem. anal.;

DOI:10.1002/ejic.200600848

upstream raw materials:

2-hydroxybromobenzene

Chlorodiisopropylphosphane

N-dimethylaminodiisopropylphosphine

Downstream raw materials:

butyldiisopropylphosphine

2-bromophenyl trimethylsilyl ether

diisopropylphenylphosphane

(1Z,5Z-cyclooctadiene)Rh(Cl)(2-Br-phenyl-O-(diisopropylphosphinite))