Cycloocta-1,5-diene;dichloroplatinum

Base Information

• Chemical Name: Cycloocta-1,5-diene;dichloroplatinum
• CAS No.: 12080-32-9
• Molecular Formula: C8H12Cl2Pt
• Molecular Weight: 374.169
• Hs Code.: 28439000
• European Community (EC) Number: 235-144-5
• Wikipedia: Dichloro(cycloocta-1,5-diene)platinum(II)
• Mol file: 12080-32-9.mol

Synonyms:12080-32-9;BCP22517;FT-0694944

Chemical Property of Cycloocta-1,5-diene;dichloroplatinum

Chemical Property:

• Appearance/Colour: white to pale yellow crystalline powder
• Vapor Pressure: 4.25mmHg at 25°C
• Melting Point: 285 °C (dec.)(lit.)
• Boiling Point: 153.5 °C at 760 mmHg
• Flash Point: 31.7 °C
• PSA: 0.00000
• LogP: 3.55730
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Sensitive.: Hygroscopic
• Solubility.: Soluble in dichloromethane
• Water Solubility.: insoluble
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 0
• Exact Mass: 372.996400
• Heavy Atom Count: 11
• Complexity: 75.4

Purity/Quality:

99.0% ^*data from raw suppliers

Dichloro[(1,2,5,6-η)-1,5-cyclooctadiene]-platinum ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39

MSDS Files:

Useful:

• Chemical Classes: Metals -> Organic Compounds, Metal Salts
• Canonical SMILES: C1CC=CCCC=C1.Cl[Pt]Cl
• Uses: it is used in Hydrosilyation reactions. Catalyst for:Hydrogenative cyclization of allenynesStereoselective tandem hydrosilylation-Hiyama coupling reactionsAmino alkene cyclohydroaminationHydrative cyclization reactionsDirect amination of allylic alcohols under mild conditionsPotential anticancer agent

Technology Process of Cycloocta-1,5-diene;dichloroplatinum

There total 41 articles about Cycloocta-1,5-diene;dichloroplatinum which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

C24H45Cl2CoOP2PtSi2 → dichloro( 1,5-cyclooctadiene)platinum(ll) (12080-32-9)

Guidance literature:

With trifluoroacetic acid; In methanol; at 20 ℃; Inert atmosphere;

DOI:10.1002/ejic.201801181

Reference yield: 95.0%

potassium tetrachloroplatinate(II) (10025-99-7) + cyclo-octa-1,5-diene (5259-72-3,10060-40-9,111-78-4) → dichloro( 1,5-cyclooctadiene)platinum(ll) (12080-32-9)

Guidance literature:

In water; acetic acid; at 110 ℃; for 3h;

DOI:10.1002/asia.201800125

Reference yield: 93.0%

cis-[bis(methyl p-tolyl sulfoxide) platinum(II) dichloride complex] (143168-86-9,198292-41-0,942128-84-9,127139-88-2,127182-40-5,265315-54-6) + cyclo-octa-1,5-diene (5259-72-3,10060-40-9,111-78-4) → dichloro( 1,5-cyclooctadiene)platinum(ll) (12080-32-9)

Guidance literature:

In dichloromethane; Irradiation (UV/VIS); mixt. soln. Pt complex and ligand in CH2Cl2 was irradiated (DRL-400 medium-pressure mercury-quartz burner) for 41 min and kept in dark for 4 h; soln. was poured into cyclohexane, ppt. was filtered off and dried in air;

DOI:10.1007/s11176-005-0224-z

upstream raw materials:

1,5-cis,cis-cyclooctadiene

dichlorobis(diethyl sulfide)platinum

cyclo-octa-1,5-diene

cis-dichlorobis(η(2)styrene)platinum(II)

Downstream raw materials:

[1,1'-bis(diphenylphosphino)ferrocene]platinum(II) chloride

Pt(HNC(O)NH)(P(C₆H₅)3)2

cis-Cl₂Pt((2-(2-methoxyethoxy)ethyl)diphenylphosphine)2

cis-bis(3,5-dimethylbenzyl)(1,5-cyclooctadiene)platinum(II)

Refernces

• 1、 Frei, Angelo,Ramu, Soumya,Lowe, Gabrielle J.,Dinh, Hue,Semenec, Lucie,Elliott, Alysha G.,Zuegg, Johannes,Deckers, Anke,Jung, Nicole,Br?se, Stefan,Cain, Amy K.,Blaskovich, Mark A. T.. "Platinum Cyclooctadiene Complexes with Activity against Gram-positive Bacteria". . p. 3165 - 3171. Retrieved 2021.
• 2、 Wu, Jianguo,Sharp, Paul R.. "CO, isocyanide, alkene, and alkyne insertions into platinaoxetane Pt-O bonds". . p. 4810 - 4816. Retrieved 2008.
• 3、 Shelton, Abigail H.,Valandro, Silvano R.,Price, Randi S.,Dubinina, Galyna G.,Abboud, Khalil A.,Wicks, Geoffrey,Rebane, Aleksander,Younus, Muhammad,Schanze, Kirk S.. "Stereochemical Effects on Platinum Acetylide Two-Photon Chromophores". . p. 9382 - 9393. Retrieved 2019.
• 4、 Mueller, Thomas E.,Ingold, Florent,Menzer, Stefan,Mingos, D. Michael P.,Williams, David J.. "Platinum(I) dimers and platinum(0) triangles with polyaromatic phosphine ligands". . p. 163 - 178. Retrieved 1997.
• 5、 Gama, Sofia,Rodrigues, Inês,Mendes, Filipa,Santos, Isabel C.,Gabano, Elisabetta,Klejevskaja, Beata,Gonzalez-Garcia, Jorge,Ravera, Mauro,Vilar, Ramon,Paulo, António. "Anthracene-terpyridine metal complexes as new G-quadruplex DNA binders". . p. 275 - 286. Retrieved 2016.
• 6、 Yuge, Hidetaka,Miyamoto, Takeshi Ken. "A phosphane analog of nedaplatin: Preparation and structural characterization of cis-bis(trimethylphosphane)-(glycolato-O,O′)platinum(II)". . p. 105 - 110. Retrieved 1998.
• 7、 Skauge, Andrew R.L.,Shalders, Richard D.,Swaddle, Thomas W.. "High-pressure methods as a tool in organometallic syntheses: Facilitation of oxidative addition to platinum(II)". . p. 1998 - 2001. Retrieved 1996.
• 8、 Hildebrandt, Jana,Trautwein, Ralf,Kritsch, Daniel,H?fner, Norman,G?rls, Helmar,Dürst, Matthias,Runnebaum, Ingo B.,Weigand, Wolfgang. "Synthesis, characterization and biological investigation of platinum(ii) complexes with asparagusic acid derivatives as ligands". . p. 936 - 944. Retrieved 2019.
• 9、 Wu, Jianguo,Sharp, Paul R.. "A family of platinaoxetanes". . p. 1234 - 1241. Retrieved 2008.
• 10、 Harada, Akira,Yamamoto, Shyoko,Takahashi, Shigetoshi. "Preparation and properties of inclusion compounds of transition-metal complexes of cycloocta-1,5-diene and norbornadiene with cyclodextrins". . p. 2560 - 2563. Retrieved 1989.