Bafilomycin A2

Base Information

Chemical Name:Bafilomycin A2
CAS No.:88899-54-1
Molecular Formula:C₃₆H₆₀O₉
Molecular Weight:636.867
Hs Code.:
DSSTox Substance ID:DTXSID701017700
ChEMBL ID:CHEMBL299049
Mol file:88899-54-1.mol

Synonyms:Bafilomycin A2;CHEMBL299049;DTXSID701017700;88899-54-1

Suppliers and Price of Bafilomycin A2

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 0 raw suppliers

Chemical Property of Bafilomycin A2

Chemical Property:

PSA：123.91000
LogP:5.34680
XLogP3:6
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:8
Exact Mass:636.42373349
Heavy Atom Count:45
Complexity:1080

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CC(=CC=CC(C(OC(=O)C(=CC(=CC(C1O)C)C)OC)C(C)C(C(C)C2(CC(C(C(O2)C(C)C)C)O)OC)O)OC)C
Isomeric SMILES:C[C@H]1C/C(=C/C=C/[C@@H]([C@H](OC(=O)/C(=C/C(=C/[C@H]([C@H]1O)C)/C)/OC)[C@@H](C)[C@H]([C@H](C)[C@]2(C[C@H]([C@@H]([C@H](O2)C(C)C)C)O)OC)O)OC)/C

Technology Process of Bafilomycin A2

There total 4 articles about Bafilomycin A2 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 67-56-1
methanol

: 88899-55-2
bafilomycin A₁

: 88899-54-1
bafilomycin A2

Guidance literature:: With pyridinium p-toluenesulfonate; for 1h;
DOI:10.1016/S0040-4039(00)73508-8

Reference yield: 50.0%

: 158227-86-2
iso-bafilomycin A₂

: 88899-54-1
bafilomycin A2

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; dichloromethane; for 168h;
DOI:10.1016/S0040-4039(00)73508-8

Reference yield:

: 158227-84-0
7,21-di-O-trimethylsilyl bafilomycin A₂

: 88899-54-1
bafilomycin A2

Guidance literature:: Multi-step reaction with 3 steps

1: 94 percent / MeLi/CuI reagent / tetrahydrofuran / 0.25 h / 0 °C

2: 69 percent / Bu₄NF / CH₂Cl₂; tetrahydrofuran

3: 50 percent / Bu₄NF / CH₂Cl₂; tetrahydrofuran / 168 h

With copper(l) iodide; tetrabutyl ammonium fluoride; methyllithium; In tetrahydrofuran; dichloromethane;
DOI:10.1016/S0040-4039(00)73508-8