Benzenemethanamine, N-(phenylmethyl)-, lithium salt

Base Information

• Chemical Name: Benzenemethanamine, N-(phenylmethyl)-, lithium salt
• CAS No.: 85175-35-5
• Molecular Formula: C14H15N.Li
• Molecular Weight: 203.213
• Mol file: 85175-35-5.mol

Synonyms:

Chemical Property of Benzenemethanamine, N-(phenylmethyl)-, lithium salt

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzenemethanamine, N-(phenylmethyl)-, lithium salt

There total 2 articles about Benzenemethanamine, N-(phenylmethyl)-, lithium salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

dibenzylamine (103-49-1) → lithium dibenzylamide (85175-35-5)

Guidance literature:

With n-butyllithium; In hexane; for 0.25h;

DOI:10.1039/c39840000285

Reference yield:

n-butyllithium (109-72-8,29786-93-4) + dibenzylamine (103-49-1) → lithium dibenzylamide (85175-35-5)

Guidance literature:

In tetrahydrofuran; hexane; at -78 ℃; for 0.5h; Inert atmosphere;

DOI:10.1016/j.tet.2015.05.019

Reference yield: 93.0%

benzyl bromide (100-39-0) + 4,4-dimethyl-2-(naphthalene-1-yl)-4,5-dihydrooxazole (87306-64-7) + lithium dibenzylamide (85175-35-5) → Dibenzyl-[(1R,4S)-4-benzyl-4-(4,4-dimethyl-4,5-dihydro-oxazol-2-yl)-1,4-dihydro-naphthalen-1-yl]-amine

Guidance literature:

4,4-dimethyl-2-(naphthalene-1-yl)-4,5-dihydrooxazole; lithium dibenzylamide; With N,N,N,N,N,N-hexamethylphosphoric triamide; In tetrahydrofuran;

benzyl bromide;

DOI:10.1021/jo960874x

upstream raw materials:

dibenzylamine

n-butyllithium

Downstream raw materials:

methyl-3-(N,N-dibenzylamino)-3-phenylpropanoate

(4S,3'R)-3-[3'-(N,N-dibenzylamino)-3'-phenylpropanoyl]-4-benzyloxazolidin-2-one

(+)-(1'S,2'S,3R)-3-dibenzylamino-N-methyl-N-(2'-phenyl-2'-hydroxy-1'-methylethyl)butanamide

(+)-(1'S,2'S,3S)-3-dibenzylamino-N,4,4-trimethyl-N-(2'-phenyl-2'-hydroxy-1'-methylethyl)pentanamide