2'-S-(4-Methoxyphenyl)-2'-thiouridine

Base Information

Chemical Name:2'-S-(4-Methoxyphenyl)-2'-thiouridine
CAS No.:85207-45-0
Molecular Formula:C16H18N2O6S
Molecular Weight:366.395
Hs Code.:
DSSTox Substance ID:DTXSID00569329
Wikidata:Q82456454

Synonyms:85207-45-0;2'-S-(4-Methoxyphenyl)-2'-thiouridine;DTXSID00569329

Suppliers and Price of 2'-S-(4-Methoxyphenyl)-2'-thiouridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2'-S-(4-Methoxyphenyl)-2'-thiouridine

Chemical Property:

XLogP3:0.9
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:5
Exact Mass:366.08855747
Heavy Atom Count:25
Complexity:537

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)SC2C(C(OC2N3C=CC(=O)NC3=O)CO)O
Isomeric SMILES:COC1=CC=C(C=C1)S[C@@H]2[C@@H]([C@H](O[C@H]2N3C=CC(=O)NC3=O)CO)O

Technology Process of 2'-S-(4-Methoxyphenyl)-2'-thiouridine

There total 1 articles about 2'-S-(4-Methoxyphenyl)-2'-thiouridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 696-63-9
4-Methoxybenzenethiol

: 3736-77-4
2,2'-Anhydrouridine

: 85207-45-0
2'-S-(4-methoxyphenyl)-2'-thiouridine

Guidance literature:: With sodium hydride; In N,N-dimethyl-formamide; paraffin; at 65 - 70 ℃; for 24h;
DOI:10.1021/jo00034a031

Reference yield: 86.0%

: 100-39-0
benzyl bromide

: 85207-45-0
2'-S-(4-methoxyphenyl)-2'-thiouridine

: 3-N-benzyl-3',5'-di-O-benzyl-2'-S-(4-methoxyphenyl)-2'-thiouridine

Guidance literature:: 2'-S-(4-methoxyphenyl)-2'-thiouridine; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 - 20 ℃; for 1h; Inert atmosphere;

benzyl bromide; In N,N-dimethyl-formamide; mineral oil; at 20 ℃; for 4h; Inert atmosphere;
DOI:10.1016/j.tet.2016.02.063

Reference yield:

: 85207-45-0
2'-S-(4-methoxyphenyl)-2'-thiouridine

: 139705-98-9
2'-deoxy-2'-<(4-methoxyphenyl)sulfonyl>uridine

Guidance literature:: Multi-step reaction with 3 steps

1: 4-(dimethylamino)pyridine / Ambient temperature

2: 99 percent / 3-chloroperoxybenzoic acid / CH₂Cl₂ / Ambient temperature

3: 82 percent / aq. HCl / methanol / 24 h / Heating

With hydrogenchloride; dmap; 3-chloro-benzenecarboperoxoic acid; In methanol; dichloromethane;
DOI:10.1021/jo00034a031