Diisopropylsilyl bis(trifluoromethanesulfonate)

Base Information

Chemical Name:Diisopropylsilyl bis(trifluoromethanesulfonate)
CAS No.:85272-30-6
Molecular Formula:C8H14F6O6S2Si
Molecular Weight:412.403
Hs Code.:2931900090
European Community (EC) Number:628-427-3
Nikkaji Number:J267.469F
Mol file:85272-30-6.mol

Synonyms:Diisopropylsilyl bis(trifluoromethanesulfonate);[di(propan-2-yl)-(trifluoromethylsulfonyloxy)silyl] trifluoromethanesulfonate;DIISOPROPYLSILYLBIS(TRIFLUOROMETHANESULFONATE);Diisopropylsilanediyl bis(trifluoromethanesulfonate);SCHEMBL631967;Trifluoromethanesulfonic acid diisopropylsilylene ester;AKOS015913430;CS-0204393;FT-0702546;diisopropylsilyl bis( trifluoromethanesulfonate);Diisopropylsilyl bis(trifluoromethanesulfonate), 96%

Suppliers and Price of Diisopropylsilyl bis(trifluoromethanesulfonate)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
Diisopropylsilyl bis(trifluoromethanesulfonate) 96%
25g
$ 418.00

Sigma-Aldrich
Diisopropylsilyl bis(trifluoromethanesulfonate) 96%
5g
$ 95.20

Biosynth Carbosynth
Diisopropylsilyl Bis(Trifluoromethanesulfonate)
25 g
$ 875.00

Biosynth Carbosynth
Diisopropylsilyl Bis(Trifluoromethanesulfonate)
1 g
$ 70.00

Biosynth Carbosynth
Diisopropylsilyl Bis(Trifluoromethanesulfonate)
10 g
$ 400.00

Biosynth Carbosynth
Diisopropylsilyl Bis(Trifluoromethanesulfonate)
5 g
$ 250.00

Biosynth Carbosynth
Diisopropylsilyl Bis(Trifluoromethanesulfonate)
2 g
$ 120.00

Total 17 raw suppliers

Chemical Property of Diisopropylsilyl bis(trifluoromethanesulfonate)

Chemical Property:

Vapor Pressure:0.031mmHg at 25°C
Refractive Index:n20/D 1.382(lit.)
Boiling Point:85-86oC2 mm Hg(lit.)
Flash Point:>230 °F
PSA：103.50000
Density:1.396 g/mL at 25oC(lit.)
LogP:5.14260
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:12
Rotatable Bond Count:6
Exact Mass:411.99052602
Heavy Atom Count:23
Complexity:553

Purity/Quality:

98%,99%, ^*data from raw suppliers

Diisopropylsilyl bis(trifluoromethanesulfonate) 96% ^*data from reagent suppliers

Safty Information:

Pictogram(s): 3567500
Hazard Codes:C
Statements: 34-37
Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CC(C)[Si](C(C)C)(OS(=O)(=O)C(F)(F)F)OS(=O)(=O)C(F)(F)F
Physical properties bp 85–86°C/2mmHg;d 1.396 g cm?3; fp 110°C.
Uses Diisopropylsilyl bis(trifluoromethanesulfonate) has more recently been used to prepare diisopropylsilyl-linked oligonucleotide analogs. Silylation of 5'-O-(dimethoxytrityl)-2'-deoxynucleosides using diisopropylsilyl bis(trifluoromethanesulfonate) and the hindered base 2,6-di-t-butyl-4-methylpyridine (Dtbp) provided quantitative yield of 3'-O-diisopropylsilanols (eq 2). Hence, silylation of 5'-O-(dimethoxytrityl)thymidine, N6-benzoyl-2'-deoxy-5'-O- (dimethoxytrityl)adenosine, N4-benzoyl-2'-deoxy-5'-O-(dimethoxytrityl) cytidine, and N2-isobutyryl-2'-deoxy-5'-O-(dimethoxytrityl) guanosine gave the desired products 5a–d in excellent yields.Coupling of products 5a–d with unprotected thymidine resulted in formation of 3',5'-linked dinucleosides 6a–d selectively, and the dimer 7 from reaction with secondary hydroxyl group of thymidine was not observed (eq 3). Subsequent silylation and coupling with another molecule of thymidine gave 3,5- linked trinucleoside 8 in 76% yield (eq 4). A tetrathymidylate oligomer was prepared by 3'-O-silylation of 8 followed by coupling with thymidine. Although no self-condensation was observed, only 30% of the product 9 was obtained after purification by preparative HPLC.

Technology Process of Diisopropylsilyl bis(trifluoromethanesulfonate)

There total 2 articles about Diisopropylsilyl bis(trifluoromethanesulfonate) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%