Diisopropyldichlorosilane

Base Information

Chemical Name:Diisopropyldichlorosilane
CAS No.:7751-38-4
Molecular Formula:C6H14Cl2Si
Molecular Weight:185.169
Hs Code.:29319090
European Community (EC) Number:629-177-8
DSSTox Substance ID:DTXSID00374298
Nikkaji Number:J364.752H
Wikidata:Q82162827
Mol file:7751-38-4.mol

Synonyms:Dichlorodiisopropylsilane;dichloro[bis(1-methylethyl)]silane;

Suppliers and Price of Diisopropyldichlorosilane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Diisopropyldichlorosilane
500mg
$ 90.00

TRC
Diisopropyldichlorosilane
50mg
$ 45.00

TCI Chemical
Dichlorodiisopropylsilane >98.0%(GC)
5g
$ 32.00

TCI Chemical
Dichlorodiisopropylsilane >98.0%(GC)
25g
$ 101.00

Sigma-Aldrich
Dichlorodiisopropylsilane ≥97.0% (GC)
25ml
$ 330.00

Sigma-Aldrich
Dichlorodiisopropylsilane ≥97.0% (GC)
5ml
$ 100.00

Oakwood
Diisopropyldichlorosilane
5g
$ 28.00

Oakwood
Diisopropyldichlorosilane
1g
$ 14.00

Oakwood
Diisopropyldichlorosilane 97%
25g
$ 84.00

Frontier Specialty Chemicals
Diisopropyldichlorosilane 97%
5g
$ 81.00

Total 49 raw suppliers

Chemical Property of Diisopropyldichlorosilane

Chemical Property:

Vapor Pressure:2.81mmHg at 25°C
Melting Point:<0°C
Refractive Index:n20/D 1.444
Boiling Point:162.6 °C at 760 mmHg
Flash Point:45.3 °C
PSA：0.00000
Density:0.991 g/cm³
LogP:3.72620
Solubility.:sol most organic solvents.
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:0
Rotatable Bond Count:2
Exact Mass:184.0241824
Heavy Atom Count:9
Complexity:79.1

Purity/Quality:

98% ^*data from raw suppliers

Diisopropyldichlorosilane ^*data from reagent suppliers

Safty Information:

Pictogram(s): C
Hazard Codes:C
Statements: 10-34
Safety Statements: 28-36/37/39-45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)[Si](C(C)C)(Cl)Cl
Physical properties bp 50–55°C/5 mmHg.
Uses Dichlorodiisopropylsilane can be used in nucleoside 3',5'-hydroxy protection; component in Peterson alkenation reaction.The use of silicon groups as protection for hydroxy groups has been widely exploited.3 One potentially useful way to protect a nucleoside is by using a protecting group which spans the 3- and 5-hydroxy groups. One of the useful groups which can be used as a bifunctional protecting group in nucleosides is the diisopropylsilyl group. Reaction of the nucleoside with dichlorodiisopropylsilane and imidazole in DMF gives the protected nucleoside (eq 1).This method has not been widely used; the more common 3',5'-hydroxy-bridging protecting group is a tetraisopropyldisiloxy group.

Technology Process of Diisopropyldichlorosilane

There total 7 articles about Diisopropyldichlorosilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%