6-Methylpyridine-3-boronic Acid

Base Information

Chemical Name:6-Methylpyridine-3-boronic Acid
CAS No.:659742-21-9
Molecular Formula:C6H8BNO2
Molecular Weight:136.946
Hs Code.:29333990
European Community (EC) Number:689-887-9
DSSTox Substance ID:DTXSID00984457
Wikidata:Q72496512
Mol file:659742-21-9.mol

Synonyms:2-methylpyridine-5-boronic acid;Boronicacid, (6-methyl-3-pyridinyl)- (9CI);(2-Methylpyridin-5-yl)boronic acid;(6-Methyl-3-pyridinyl)boronic acid;2-Picoline-5-boronic acid;

Suppliers and Price of 6-Methylpyridine-3-boronic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
2-Methylpyridine-5-boronic acid
500mg
$ 453.00

TRC
6-Methylpyridine-3-boronic acid
250mg
$ 45.00

Synthonix
(6-Methylpyridin-3-yl)boronicacid 97%
10g
$ 220.00

Synthonix
(6-Methylpyridin-3-yl)boronicacid 97%
5g
$ 120.00

Synthonix
(6-Methylpyridin-3-yl)boronicacid 97%
1g
$ 40.00

Synthonix
(6-Methylpyridin-3-yl)boronicacid 97%
250mg
$ 20.00

SynChem
2-Methyl-5-pyridinyl boronic acid 95%
1 g
$ 105.00

SynChem
2-Methyl-5-pyridinyl boronic acid 95%
5 g
$ 340.00

SynChem
2-Methyl-5-pyridinyl boronic acid 95%
10 g
$ 580.00

Sigma-Aldrich
6-Methylpyridine-3-boronic acid
500mg
$ 112.00

Total 117 raw suppliers

Chemical Property of 6-Methylpyridine-3-boronic Acid

Chemical Property:

Appearance/Colour:white or yellow crystal
Vapor Pressure:0.001mmHg at 25°C
Refractive Index:1.528
Boiling Point:294.7 °C at 760 mmHg
PKA:4.27±0.10(Predicted)
Flash Point:132 °C
PSA：53.35000
Density:1.18 g/cm³
LogP:-0.93020
Storage Temp.:2-8°C
Solubility.:DMSO (Slightly), Methanol (Slightly)
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:137.0648087
Heavy Atom Count:10
Complexity:110

Purity/Quality:

99% ^*data from raw suppliers

2-Methylpyridine-5-boronic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B(C1=CN=C(C=C1)C)(O)O
Uses 6-Methylpyridine-3-boronic Acid is used in the preparation of various biologically active compound such as phosphoinositide-3-kinases (PI3K) and c-jun N-terminal kinase (JNK) inhibitors. suzuki reaction

Technology Process of 6-Methylpyridine-3-boronic Acid

There total 5 articles about 6-Methylpyridine-3-boronic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 111770-91-3
(6-methylpyridin-3-yl)trifluoromethanesulfonate

: 73183-34-3
bis(pinacol)diborane

: 659742-21-9
(6-methylpyridin-3-yl)boronic acid

Guidance literature:: With potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In acetonitrile; at 160 ℃; for 0.333333h; Microwave;

Reference yield: 61.0%

: 3430-13-5
5-bromo-2-methylpyridine

: 5419-55-6
Triisopropyl borate

: 659742-21-9
(6-methylpyridin-3-yl)boronic acid

Guidance literature:: With n-butyllithium; In tetrahydrofuran; hexane; toluene; at -78 ℃; for 1.5h; Inert atmosphere; Schlenk technique;
DOI:10.1039/c4tc00542b

Reference yield:

: 3430-13-5
5-bromo-2-methylpyridine

: 659742-21-9
(6-methylpyridin-3-yl)boronic acid

Guidance literature:: 5-bromo-2-methylpyridine; With n-butyllithium; In diethyl ether; hexane; at -78 ℃; for 1.66667h; Inert atmosphere;

With Triisopropyl borate; In diethyl ether; hexane; at -78 - 20 ℃;