3,6-dibromo-9-(oxiran-2-ylmethyl)-9H-carbazole

Base Information

• Chemical Name: 3,6-dibromo-9-(oxiran-2-ylmethyl)-9H-carbazole
• CAS No.: 85446-05-5
• Molecular Formula: C15H11Br2NO
• Molecular Weight: 381.066
• Hs Code.: 2933990090
• European Community (EC) Number: 866-848-6
• DSSTox Substance ID: DTXSID30379559
• Nikkaji Number: J1.133.478D
• ChEMBL ID: CHEMBL1408168
• Mol file: 85446-05-5.mol

Synonyms:3,6-dibromo-9-(oxiran-2-ylmethyl)-9H-carbazole;85446-05-5;3,6-dibromo-9-(oxiran-2-ylmethyl)carbazole;3,6-DIBROMO-9-[(OXIRAN-2-YL)METHYL]-9H-CARBAZOLE;9H-Carbazole, 3,6-dibromo-9-(oxiranylmethyl)-;MFCD00218277;3,6-dibromo-9-oxiranylmethyl-9h-carbazole;SCHEMBL409341;CHEMBL1408168;3,6-Dibromo-9-glycidylcarbazole;DTXSID30379559;DGMRGIDWASSLGY-UHFFFAOYSA-N;3,6-Dibromo-9-glycidyl-9H-carbazole;AKOS003390672;NCGC00161080-01;NCGC00161080-02;AS-66646;3,6-Dibromo-N-(2,3-epoxypropyl)carbazole;EN300-69887;W18013;3,6-dibromo-9-(2-oxiranylmethyl)-9H-carbazole;A918059;(+/-)-3,6-Dibromo-9-(oxiran-2-ylmethyl)carbazole;F1913-8642;Z276654594

Chemical Property of 3,6-dibromo-9-(oxiran-2-ylmethyl)-9H-carbazole

Chemical Property:

• Boiling Point: 503.8±43.0 °C(Predicted)
• PSA: 17.46000
• Density: 1.88±0.1 g/cm3(Predicted)
• LogP: 4.71830
• XLogP3: 4.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 380.91869
• Heavy Atom Count: 19
• Complexity: 327

Purity/Quality:

97% ^*data from raw suppliers

3,6-Dibromo-9-(oxiran-2-ylmethyl)-9H-carbazole 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1C(O1)CN2C3=C(C=C(C=C3)Br)C4=C2C=CC(=C4)Br

Technology Process of 3,6-dibromo-9-(oxiran-2-ylmethyl)-9H-carbazole

There total 7 articles about 3,6-dibromo-9-(oxiran-2-ylmethyl)-9H-carbazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.7%

3,6-dibromo-9H-carbazole (6825-20-3) + 1,2-Epoxy-3-bromopropane (3132-64-7,82584-73-4) → 3,6-dibromo-9-(oxiran-2-ylmethyl)-9H-carbazole (85446-05-5)

Guidance literature:

3,6-dibromo-9H-carbazole; With potassium hydroxide; In N,N-dimethyl-formamide; at 20 ℃; for 1h;

1,2-Epoxy-3-bromopropane; In N,N-dimethyl-formamide; at 20 ℃; for 3h;

Reference yield: 65.0%

3,6-dibromo-9H-carbazole (6825-20-3) + oxiranyl-methanol (556-52-5) → 3,6-dibromo-9-(oxiran-2-ylmethyl)-9H-carbazole (85446-05-5)

Guidance literature:

With triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; at 20 ℃;

DOI:10.1021/jm034107j

Reference yield: 65.0%

3,6-dibromo-9H-carbazole (6825-20-3) + oxiranyl-methanol (556-52-5) → 3,6-dibromo-9-(oxiran-2-ylmethyl)-9H-carbazole (85446-05-5) + C27H16Br4N2

Guidance literature:

With triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; at 25 ℃; for 15h;

DOI:10.1016/S0040-4039(02)00217-4

upstream raw materials:

3,6-dibromo-9H-carbazole

oxiranyl-methanol

epichlorohydrin

1,2-Epoxy-3-bromopropane

Downstream raw materials:

C₂₇H₂₁Br₂N₃O₅S

1-(3,6-dibromo-9H-carbazol-9-yl)-3-((3-methoxyphenyl)(methyl)amino)propan-2-ol

N-(3-(3,6-dibromo-9H-carbazol-9-yl)-2-fluoropropyl)-3-methoxy-N-methylaniline

1-(3-azidophenylamino)-3-(3,6-dibromo-9H-carbazol-9-yl)propan-2-ol