PHENYLSULFONYL-L-SERINE

Base Information

• Chemical Name: PHENYLSULFONYL-L-SERINE
• CAS No.: 85828-29-1
• Molecular Formula: C9H11NO5S
• Molecular Weight: 245.256
• Hs Code.: 2935009090
• Mol file: 85828-29-1.mol

Synonyms:N-benzenesulfonyl-L-serine;

Chemical Property of PHENYLSULFONYL-L-SERINE

Chemical Property:

• PSA: 112.08000
• LogP: 0.88210

Purity/Quality:

97% ^*data from raw suppliers

(2S)-2-BENZENESULFONAMIDO-3-HYDROXYPROPANOIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of PHENYLSULFONYL-L-SERINE

There total 2 articles about PHENYLSULFONYL-L-SERINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.1%

L-serin (56-45-1,83245-15-2) + benzenesulfonyl chloride (98-09-9) → 3-hydroxy-2-[(phenylsulfonyl)amino]propanoic acid (85828-29-1)

Guidance literature:

With NaCO₃; In water; for 4h;

DOI:10.1021/ja00316a047

Reference yield:

→ 3-hydroxy-2-[(phenylsulfonyl)amino]propanoic acid (85828-29-1)

Guidance literature:

Reference yield: 96.4%

propylamine (107-10-8,42939-71-9) + 3-hydroxy-2-[(phenylsulfonyl)amino]propanoic acid (85828-29-1) → 3-hydroxy-2-[(phenylsulphonyl)amino]-N-propylpropanamide

Guidance literature:

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; In toluene; for 12h; Dean-Stark; Reflux;

DOI:10.1016/j.bioorg.2019.103265

upstream raw materials:

L-serin

benzenesulfonyl chloride

Downstream raw materials:

(S)-α-(N-(phenylsulfonyl)amino)-β-hydroxy-3,4-dimethoxypropiophenone

(S)-2-(N-(phenylsulfonyl)amino)-3-oxo-1,7-dihydroxyheptane

(S)-3-(N-(phenylsulfonyl)amino)-4-hydroxy-2-butanone

(S)-2-(N-(phenylsulfonyl)amino)-1-hydroxy-3-hexanone