4,4-Dimethyl-2-[2-(methylsulfanyl)phenyl]-4,5-dihydro-1,3-oxazole

Base Information

Chemical Name:4,4-Dimethyl-2-[2-(methylsulfanyl)phenyl]-4,5-dihydro-1,3-oxazole
CAS No.:86065-02-3
Molecular Formula:C12H15NOS
Molecular Weight:221.323
Hs Code.:
DSSTox Substance ID:DTXSID80516331
Wikidata:Q82377711

Synonyms:4,4-dimethyl-2-[2-(methylsulfanyl)phenyl]-4,5-dihydro-1,3-oxazole;86065-02-3;DTXSID80516331;4,4-dimethyl-2-(2-methylsulfanyl-phenyl)-5H-oxazole

Suppliers and Price of 4,4-Dimethyl-2-[2-(methylsulfanyl)phenyl]-4,5-dihydro-1,3-oxazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4,4-Dimethyl-2-[2-(methylsulfanyl)phenyl]-4,5-dihydro-1,3-oxazole

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:221.08743528
Heavy Atom Count:15
Complexity:262

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(COC(=N1)C2=CC=CC=C2SC)C

Technology Process of 4,4-Dimethyl-2-[2-(methylsulfanyl)phenyl]-4,5-dihydro-1,3-oxazole

There total 2 articles about 4,4-Dimethyl-2-[2-(methylsulfanyl)phenyl]-4,5-dihydro-1,3-oxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 30093-99-3
4,4-dimethyl-2-oxazoline

: 86065-02-3
2-<2-(methylthio)phenyl>-4,4-dimethyloxazoline

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) n-BuLi / 1.) glyme, 0 deg C, 15 min, 2.) reflux, 20 h

2: 1.) diisopropylamine, n-BuLi / 1.) THF, 6 h, reflux, 2.) room temp.

With n-butyllithium; diisopropylamine;
DOI:10.1021/jo00163a041

Reference yield:

: 86064-95-1
4,4-dimethyl-2-(phenylthio)-4,5-dihydrooxazole

: 74-88-4
methyl iodide

: 86065-02-3
2-<2-(methylthio)phenyl>-4,4-dimethyloxazoline

Guidance literature:: With n-butyllithium; diisopropylamine; Yield given. Multistep reaction; 1.) THF, 6 h, reflux, 2.) room temp.;
DOI:10.1021/jo00163a041