N~1~-[2-(Pyrrolidin-1-yl)ethyl]benzene-1,4-diamine

Base Information

Chemical Name:N~1~-[2-(Pyrrolidin-1-yl)ethyl]benzene-1,4-diamine
CAS No.:863453-84-3
Molecular Formula:C12H19N3
Molecular Weight:205.303
Hs Code.:
DSSTox Substance ID:DTXSID00582119
Wikidata:Q82473442

Synonyms:863453-84-3;N~1~-[2-(Pyrrolidin-1-yl)ethyl]benzene-1,4-diamine;SCHEMBL2259794;DTXSID00582119;HDWIOQFBQKXYBZ-UHFFFAOYSA-N;AKOS011934934;(4-aminophenyl)[2-(1-pyrrolidinyl)ethyl]amine;N-(2-Pyrrolidin-1-yl-ethyl)-benzene-1,4-diamine

Suppliers and Price of N~1~-[2-(Pyrrolidin-1-yl)ethyl]benzene-1,4-diamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N~1~-[2-(Pyrrolidin-1-yl)ethyl]benzene-1,4-diamine

Chemical Property:

XLogP3:1.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:205.157897619
Heavy Atom Count:15
Complexity:170

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN(C1)CCNC2=CC=C(C=C2)N

Technology Process of N~1~-[2-(Pyrrolidin-1-yl)ethyl]benzene-1,4-diamine

There total 4 articles about N~1~-[2-(Pyrrolidin-1-yl)ethyl]benzene-1,4-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 863453-76-3
(4-nitrophenyl)-(2-pyrrolidin-1-ylethyl)amine

: 863453-84-3
N-(2-pyrrolidin-1-ylethyl)benzene-1,4-diamine

Guidance literature:: With hydrazine; nickel; In ethanol; at 65 ℃; for 1h;

Reference yield:

: 100-00-5
4-chlorobenzonitrile

: 863453-84-3
N-(2-pyrrolidin-1-ylethyl)benzene-1,4-diamine

Guidance literature:: Multi-step reaction with 4 steps

1: 36 percent / 3 h / 40 °C

2: TEA / CH₂Cl₂ / 0.5 h / 0 - 20 °C

3: 86 percent / TEA; DBU / CH₂Cl₂ / 70 h

4: 125 mg / hydrazine hydrate / Pd/C / Heating

With TEA; hydrazine hydrate; 1,8-diazabicyclo[5.4.0]undec-7-ene; palladium on activated charcoal; In dichloromethane;
DOI:10.1021/jm060262x

Reference yield:

: 100418-51-7
2-((4-nitrophenyl)amino)ethyl methanesulfonate

: 863453-84-3
N-(2-pyrrolidin-1-ylethyl)benzene-1,4-diamine

Guidance literature:: Multi-step reaction with 2 steps

1: 86 percent / TEA; DBU / CH₂Cl₂ / 70 h

2: 125 mg / hydrazine hydrate / Pd/C / Heating

With TEA; hydrazine hydrate; 1,8-diazabicyclo[5.4.0]undec-7-ene; palladium on activated charcoal; In dichloromethane;
DOI:10.1021/jm060262x