ethyl 2-oxo-2-(5-phenylmethoxy-1H-indol-3-yl)acetate

Base Information

Chemical Name:ethyl 2-oxo-2-(5-phenylmethoxy-1H-indol-3-yl)acetate
CAS No.:75238-44-7
Molecular Formula:C19H17NO4
Molecular Weight:323.34
Hs Code.:
NSC Number:75566
DSSTox Substance ID:DTXSID70291443
Wikidata:Q82029405
Mol file:75238-44-7.mol

Synonyms:75238-44-7;ethyl 2-oxo-2-(5-phenylmethoxy-1H-indol-3-yl)acetate;Ethyl 5-benzyloxyindole-3-glyoxylate;Ethyl 2-[5-(Benzyloxy)-3-indolyl]-2-oxoacetate;5-benzyloxyindole-3-glyoxylic acid ethyl ester;Ethyl5-benzyloxyindole-3-glyoxylate;NSC75566;NCIOpen2_008431;ethyl 2-(5-(benzyloxy)-1H-indol-3-yl)-2-oxoacetate;SCHEMBL11620503;DTXSID70291443;GEOTYZHKCQCORI-UHFFFAOYSA-N;AC6751;ethyl 5-benzyloxy-3-indoleglyoxalate;MFCD00022723;NSC-75566;SY058567;FT-0620050;B-2050;B-2052;A838357;Ethyl [5-(benzyloxy)-1H-indol-3-yl](oxo)acetate;2-oxo-2-(5-phenylmethoxy-1H-indol-3-yl)acetic acid ethyl ester;ethyl 2-(5-benzyloxy-1H-indol-3-yl)-2-oxo-acetate

Suppliers and Price of ethyl 2-oxo-2-(5-phenylmethoxy-1H-indol-3-yl)acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
α-?Oxo-?5-?(phenylmethoxy)?-?1H-?indole-?3-?aceticAcidEthylEster
25mg
$ 1705.00

TRC
α-?Oxo-?5-?(phenylmethoxy)?-?1H-?indole-?3-?aceticAcidEthylEster
5mg
$ 400.00

American Custom Chemicals Corporation
5-BENZYLOXYINDOLE-3-GLYOXYLIC ACID ETHYL ESTER 95.00%
250MG
$ 648.83

American Custom Chemicals Corporation
5-BENZYLOXYINDOLE-3-GLYOXYLIC ACID ETHYL ESTER 95.00%
1G
$ 848.93

AK Scientific
Ethyl2-oxo-2-(5-phenylmethoxy-1H-indol-3-yl)acetate
5g
$ 1072.00

AHH
Ethyl5-benzyloxyindole-3-glyoxylate 97%
5g
$ 688.00

Total 12 raw suppliers

Chemical Property of ethyl 2-oxo-2-(5-phenylmethoxy-1H-indol-3-yl)acetate

Chemical Property:

Vapor Pressure:5.87E-11mmHg at 25°C
Refractive Index:1.631
Boiling Point:521.1 °C at 760 mmHg
Flash Point:268.9 °C
PSA：68.39000
Density:1.269 g/cm³
LogP:3.49270
Storage Temp.:Room Temperature
Solubility.:Methanol, THF
XLogP3:3.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:323.11575802
Heavy Atom Count:24
Complexity:447

Purity/Quality:

97% ^*data from raw suppliers

α-?Oxo-?5-?(phenylmethoxy)?-?1H-?indole-?3-?aceticAcidEthylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(=O)C1=CNC2=C1C=C(C=C2)OCC3=CC=CC=C3
Uses α-?Oxo-?5-?(phenylmethoxy)?-?1H-?indole-?3-?acetic Acid Ethyl Ester is an intermediate in synthesizing 5-Hydroxy Tryptophol-d4 β-D-Glucuronide (H976012), a labelled metabolite of 5-Hydroxytryptamine (H974990).

Technology Process of ethyl 2-oxo-2-(5-phenylmethoxy-1H-indol-3-yl)acetate

There total 3 articles about ethyl 2-oxo-2-(5-phenylmethoxy-1H-indol-3-yl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 22424-61-9
2-[5-(benzyloxy)-1H-indol-3-yl]-2-oxoacetyl chloride

: 141-52-6
sodium ethanolate

: 75238-44-7
(5-benzyloxy-indol-3-yl)-glyoxylic acid ethyl ester

Guidance literature:: In tetrahydrofuran; diethyl ether; ethanol; at -60 - 20 ℃;
DOI:10.1021/ja068969w

Reference yield:

: 1215-59-4
5-benzyloxy-1H-indole

: 75238-44-7
(5-benzyloxy-indol-3-yl)-glyoxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: diethyl ether; tetrahydrofuran / 0 - 20 °C

2: diethyl ether; tetrahydrofuran; ethanol / -60 - 20 °C

In tetrahydrofuran; diethyl ether; ethanol;
DOI:10.1021/ja068969w