2H-Indol-2-one, 4-fluoro-1,3-dihydro-3,3-dimethyl-

Base Information

Chemical Name:2H-Indol-2-one, 4-fluoro-1,3-dihydro-3,3-dimethyl-
CAS No.:866211-50-9
Molecular Formula:C10H10FNO
Molecular Weight:179.19100
Hs Code.:

Synonyms:2H-Indol-2-one,4-fluoro-1,3-dihydro-3,3-dimethyl;4-fluoro-3,3-dimethyl-1,3-dihydro-2H-indol-2-one;5-fluoro-3,3-dimethyl-1,3-dihydroindol-2-one;4-FLUORO-3,3-DIMETHYLINDOLIN-2-ONE;

Suppliers and Price of 2H-Indol-2-one, 4-fluoro-1,3-dihydro-3,3-dimethyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
4-Fluoro-3,3-dimethylindolin-2-one 97%
1g
$ 857.00

Chemenu
4-Fluoro-3,3-dimethylindolin-2-one 95%+
1g
$ 809.00

Alichem
4-Fluoro-3,3-dimethylindolin-2-one
1g
$ 1011.21

Total 1 raw suppliers

Chemical Property of 2H-Indol-2-one, 4-fluoro-1,3-dihydro-3,3-dimethyl-

Chemical Property:

PSA：32.59000
LogP:2.14050

Purity/Quality:: 4-Fluoro-3,3-dimethylindolin-2-one 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2H-Indol-2-one, 4-fluoro-1,3-dihydro-3,3-dimethyl-

There total 4 articles about 2H-Indol-2-one, 4-fluoro-1,3-dihydro-3,3-dimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: methyl 2-(2-fluoro-6-nitrophenyl)-2-methylpropanoate

: 866211-50-9
4-fluoro-3,3-dimethyl-1,3-dihydro-2H-indol-2-one

Guidance literature:: With zinc; In acetic acid; at 100 ℃; for 48h;
DOI:10.1016/j.bmc.2015.10.002

Reference yield: 25.0%

: 138343-94-9
4-fluoro-1,3-dihydro-2H-indol-2-one

: 74-88-4
methyl iodide

: 866211-50-9
4-fluoro-3,3-dimethyl-1,3-dihydro-2H-indol-2-one

Guidance literature:: 4-fluoro-1,3-dihydro-2H-indol-2-one; With n-butyllithium; lithium chloride; In tetrahydrofuran; hexane; at -78 ℃; for 0.25h;

methyl iodide; In tetrahydrofuran; hexane; at 20 ℃; for 16h; Further stages.;
DOI:10.1021/jm701080t

Reference yield:

: 913720-03-3
2-(2,3-difluorophenyl)isobutyramide

: 913720-04-4
2-(2,6-difluorophenyl)isobutyramide

: 866208-24-4
7-fluoro-3,3-dimethyl-1,3-dihydro-2H-indol-2-one

: 866211-50-9
4-fluoro-3,3-dimethyl-1,3-dihydro-2H-indol-2-one

Guidance literature:: 2-(2,3-difluorophenyl)isobutyramide; 2-(2,6-difluorophenyl)isobutyramide; With lithium hydride; In N,N-dimethyl-formamide; at 120 ℃; for 7h;

With hydrogenchloride; water; In ethyl acetate; N,N-dimethyl-formamide; Product distribution / selectivity;