1-(5-Phenylpyridin-2-yl)ethan-1-one

Base Information

Chemical Name:1-(5-Phenylpyridin-2-yl)ethan-1-one
CAS No.:866326-59-2
Molecular Formula:C13H11NO
Molecular Weight:197.236
Hs Code.:
European Community (EC) Number:852-054-7

Synonyms:1-(5-phenylpyridin-2-yl)ethan-1-one;866326-59-2;1-(5-phenylpyridin-2-yl)ethanone;SCHEMBL6264166;AKOS022302356;EN300-263012;Z1255452486

Suppliers and Price of 1-(5-Phenylpyridin-2-yl)ethan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 1-(5-Phenylpyridin-2-yl)ethan-1-one

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:197.084063974
Heavy Atom Count:15
Complexity:221

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1=NC=C(C=C1)C2=CC=CC=C2

Technology Process of 1-(5-Phenylpyridin-2-yl)ethan-1-one

There total 3 articles about 1-(5-Phenylpyridin-2-yl)ethan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 98-80-6
phenylboronic acid

: 214701-49-2
1-(5-bromopyridin-2-yl)ethanone

: 866326-59-2
1-(5-phenylpyridin-2-yl)ethanone

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In water; toluene; at 105 ℃; Inert atmosphere;
DOI:10.1039/c1dt10465a

Reference yield: 54.0%

: 127-19-5,116057-81-9
N,N-dimethyl acetamide

: 107351-82-6
2-bromo-5-phenyl-pyridine

: 866326-59-2
1-(5-phenylpyridin-2-yl)ethanone

Guidance literature:: 2-bromo-5-phenyl-pyridine; With n-butyllithium; In diethyl ether; hexane; at -60 ℃; for 2h;

N,N-dimethyl acetamide; In diethyl ether; hexane; for 2h;

With hydrogenchloride; water; In diethyl ether; hexane; at 20 ℃;

Reference yield:

: 624-28-2
2,5-dibromopyridine

: 866326-59-2
1-(5-phenylpyridin-2-yl)ethanone

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium / toluene / Inert atmosphere

1.2: Inert atmosphere

2.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate / water; toluene / 105 °C / Inert atmosphere

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; n-butyllithium; potassium carbonate; In water; toluene; 2.1: Suzuki reaction;
DOI:10.1039/c1dt10465a