Ethyl 3-bromo-2-methylpropanoate

Base Information

• Chemical Name: Ethyl 3-bromo-2-methylpropanoate
• CAS No.: 59154-46-0
• Deprecated CAS: 146502-52-5
• Molecular Formula: C6H11 Br O2
• Molecular Weight: 195.056
• Hs Code.: 2915900090
• European Community (EC) Number: 261-631-7
• DSSTox Substance ID: DTXSID40275957,DTXSID10886352
• Nikkaji Number: J308.633J
• Mol file: 59154-46-0.mol

Synonyms:Ethyl 3-bromo-2-methylpropanoate;59154-46-0;Ethyl 3-bromo-2-methylpropionate;Propanoic acid, 3-bromo-2-methyl-, ethyl ester;EINECS 261-631-7;AI3-36611;SCHEMBL220652;DTXSID10886352;DTXSID40275957;3-Bromoisobutyric acid ethyl ester;Ethyl 3-bromo-2-methylpropanoate #;AKOS006273489;CS-0265062;FT-0712490;EN300-96266;146502-52-5

Chemical Property of Ethyl 3-bromo-2-methylpropanoate

Chemical Property:

• Vapor Pressure: 1.29mmHg at 25°C
• Boiling Point: 173°C at 760 mmHg
• Flash Point: 90.3°C
• PSA: 26.30000
• Density: 1.348g/cm³
• LogP: 1.58050
• XLogP3: 1.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 193.99424
• Heavy Atom Count: 9
• Complexity: 93.1

Purity/Quality:

99% ^*data from raw suppliers

ethyl 3-bromo-2-methylpropionate 97 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)C(C)CBr

Technology Process of Ethyl 3-bromo-2-methylpropanoate

There total 3 articles about Ethyl 3-bromo-2-methylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl methacrylate (97-63-2,9003-42-3) → ethyl ester of β-bromoisobutyric acid (59154-46-0)

Guidance literature:

With hydrogen bromide;

Reference yield:

3-hydroxy-2-methyl-propionic acid ethyl ester (89534-52-1) → ethyl ester of β-bromoisobutyric acid (59154-46-0)

Guidance literature:

With chloroform; phosphorus tribromide; zuletzt auf dem Dampfbad;

Reference yield:

→ ethyl ester of β-bromoisobutyric acid (59154-46-0)

Guidance literature:

Methacrylsaeure-ethylester, HBr;

upstream raw materials:

methyl methacrylate

3-hydroxy-2-methyl-propionic acid ethyl ester

Downstream raw materials:

7-bromo-2,2-dimethyl-2H-pyrido[3.2-b][1,4]oxazin-3(4H)-one

2-(4-benzyloxy-2-formylphenoxy)-2-methyl propionic acid ethyl ester

rac-ethyl 3-cyanobutanoate

3,3'-methylimino-di-propionic acid diethyl ester