2-(Dimethylamino)benzothiazol-6-ol

Base Information

• Chemical Name: 2-(Dimethylamino)benzothiazol-6-ol
• CAS No.: 943-04-4
• Molecular Formula: C9H10N2OS
• Molecular Weight: 194.257
• Hs Code.: 2934999090
• European Community (EC) Number: 213-396-7
• DSSTox Substance ID: DTXSID10241407
• Nikkaji Number: J298.546B
• Wikidata: Q83124915
• Mol file: 943-04-4.mol

Synonyms:943-04-4;2-(dimethylamino)-1,3-benzothiazol-6-ol;2-(Dimethylamino)benzothiazol-6-ol;2-Dimethylamino-6-benzothiazolol;2-(dimethylamino)benzo[d]thiazol-6-ol;2-Dimethylamino-benzothiazol-6-ol;EINECS 213-396-7;ChemDiv2_000157;EC-000.1449;Cambridge id 5195231;Oprea1_054529;Oprea1_438603;F0346-2873;SCHEMBL5536580;DTXSID10241407;PGL-137;HMS1369H03;6-Benzothiazolol,2-(dimethylamino)-;MFCD00456101;STK098197;AKOS000541752;6-Hydroxy-2-dimethylamino-benzothiazol;CCG-103796;BB 0260428;FT-0679191;EN300-235849;A917261

Chemical Property of 2-(Dimethylamino)benzothiazol-6-ol

Chemical Property:

• Vapor Pressure: 8.04E-05mmHg at 25°C
• Refractive Index: 1.726
• Boiling Point: 331.5 °C at 760 mmHg
• Flash Point: 154.3 °C
• PSA: 64.60000
• Density: 1.361 g/cm³
• LogP: 2.06790
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 194.05138412
• Heavy Atom Count: 13
• Complexity: 189

Purity/Quality:

98%Min ^*data from raw suppliers

2-(Dimethylamino)-1,3-benzothiazol-6-ol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)C1=NC2=C(S1)C=C(C=C2)O

Technology Process of 2-(Dimethylamino)benzothiazol-6-ol

There total 5 articles about 2-(Dimethylamino)benzothiazol-6-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-methoxy-N,N-dimethylbenzo[d]thiazol-2-amine (75105-03-2) → 2-dimethylamino-benzothiazol-6-ol (943-04-4)

Guidance literature:

With hydrogen bromide;

Reference yield:

2-chloro-6-(methyloxy)-1,3-benzothiazole (2605-14-3) → 2-dimethylamino-benzothiazol-6-ol (943-04-4)

Guidance literature:

Multi-step reaction with 2 steps

1: methanol

2: concentrated aqueous HI

With methanol; hydrogen iodide;

Reference yield:

(6-ethoxy-benzothiazol-2-yl)-dimethyl-amine (5304-29-0) → 2-dimethylamino-benzothiazol-6-ol (943-04-4)

Guidance literature:

With hydrogen bromide;

upstream raw materials:

6-methoxy-N,N-dimethylbenzo[d]thiazol-2-amine

(6-ethoxy-benzothiazol-2-yl)-dimethyl-amine

2-chloro-6-(methyloxy)-1,3-benzothiazole

3-(4-methoxyphenyl)-1,1-dimethylthiourea

Downstream raw materials:

Dimazole

dimethyl-[6-(2-piperidino-ethoxy)-benzothiazol-2-yl]-amine