3-Bromo-5,7-dimethyl-2-phenylpyrazolo[1,5-a]pyrimidine

Base Information

Chemical Name:3-Bromo-5,7-dimethyl-2-phenylpyrazolo[1,5-a]pyrimidine
CAS No.:87119-68-4
Molecular Formula:C14H12BrN3
Molecular Weight:302.173
Hs Code.:
DSSTox Substance ID:DTXSID20384793
Wikidata:Q82177154

Synonyms:87119-68-4;3-bromo-5,7-dimethyl-2-phenylpyrazolo[1,5-a]pyrimidine;Pyrazolo[1,5-a]pyrimidine, 3-bromo-5,7-dimethyl-2-phenyl-;HMS1440D05;Maybridge3_003239;DTXSID20384793;AKOS002684406;CCG-253209;IDI1_014626

Suppliers and Price of 3-Bromo-5,7-dimethyl-2-phenylpyrazolo[1,5-a]pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-Bromo-5,7-dimethyl-2-phenylpyrazolo[1,5-a]pyrimidine

Chemical Property:

XLogP3:3.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:301.02146
Heavy Atom Count:18
Complexity:293

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=NC2=C(C(=NN12)C3=CC=CC=C3)Br)C

Technology Process of 3-Bromo-5,7-dimethyl-2-phenylpyrazolo[1,5-a]pyrimidine

There total 4 articles about 3-Bromo-5,7-dimethyl-2-phenylpyrazolo[1,5-a]pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 87119-67-3
5,7-Dimethyl-2-phenylpyrazolo<1,5-a>pyrimidine

: 87119-68-4
3-bromo-5,7-dimethyl-2-phenylpyrazolo<1,5-a>pyrimidine

Guidance literature:: With bromine; In chloroform; for 0.25h; further reagent;
DOI:10.1002/jhet.5570210402

Reference yield: 78.0%

: 70081-28-6
5-amino-4-bromo-3-phenylpyrazole

: 123-54-6,81235-32-7
acetylacetone

: 87119-68-4
3-bromo-5,7-dimethyl-2-phenylpyrazolo<1,5-a>pyrimidine

Guidance literature:: In ethanol; for 3h; Heating;
DOI:10.1002/jhet.5570210402

Reference yield:

: 70081-28-6
5-amino-4-bromo-3-phenylpyrazole

: 87119-68-4
3-bromo-5,7-dimethyl-2-phenylpyrazolo<1,5-a>pyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: 75 percent / ethanol / 5 h / Heating

2: 85 percent / NBS / CCl₄ / 0.25 h / 50 °C

With N-Bromosuccinimide; In tetrachloromethane; ethanol;
DOI:10.1002/ardp.19833160810