Benzenesulfonamide,N,N'-1,2-phenylenebis[N,4-dimethyl-

Base Information

• Chemical Name: Benzenesulfonamide,N,N'-1,2-phenylenebis[N,4-dimethyl-
• CAS No.: 29627-62-1
• Molecular Formula: C22H24 N2 O4 S2
• Molecular Weight: 444.576
• NSC Number: 101062
• DSSTox Substance ID: DTXSID20295299
• Nikkaji Number: J946.939G
• Wikidata: Q82035153
• Pharos Ligand ID: Z5SHFTW3ZMLU
• ChEMBL ID: CHEMBL595990
• Mol file: 29627-62-1.mol

Synonyms:p-Toluenesulfonamide,N,N'-o-phenylenebis[N-methyl- (8CI); NSC 101062

Chemical Property of Benzenesulfonamide,N,N'-1,2-phenylenebis[N,4-dimethyl-

Chemical Property:

• Boiling Point: 590.7°Cat760mmHg
• Flash Point: 311°C
• Density: 1.318g/cm³
• XLogP3: 4.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 6
• Exact Mass: 444.11774960
• Heavy Atom Count: 30
• Complexity: 690

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)S(=O)(=O)N(C)C2=CC=CC=C2N(C)S(=O)(=O)C3=CC=C(C=C3)C

Technology Process of Benzenesulfonamide,N,N'-1,2-phenylenebis[N,4-dimethyl-

There total 6 articles about Benzenesulfonamide,N,N'-1,2-phenylenebis[N,4-dimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

1,2-bis-(p-methylphenylsulfonamido)-benzene (49633-28-5) + methyl iodide (74-88-4) → N,N’-dimethyl-N,N’-di(p-toluenesulfonyl)-o-phenylenediamine (29627-62-1)

Guidance literature:

1,2-bis-(p-methylphenylsulfonamido)-benzene; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 ℃; for 0.25h;

methyl iodide; In N,N-dimethyl-formamide; mineral oil; at 20 ℃; for 6h;

DOI:10.1002/anie.201207410

Reference yield: 90.0%

1,2-bis-(p-methylphenylsulfonamido)-benzene (49633-28-5) + dimethyl sulfate (77-78-1) → N,N’-dimethyl-N,N’-di(p-toluenesulfonyl)-o-phenylenediamine (29627-62-1)

Guidance literature:

1,2-bis-(p-methylphenylsulfonamido)-benzene; With sodium hydroxide; In water; at 90 - 120 ℃; for 0.5h; Inert atmosphere;

dimethyl sulfate; In water; at 20 - 120 ℃; for 2h; Inert atmosphere;

Reference yield:

1,2-bis-(p-methylphenylsulfonamido)-benzene (49633-28-5) → N,N’-dimethyl-N,N’-di(p-toluenesulfonyl)-o-phenylenediamine (29627-62-1)

Guidance literature:

With sodium hydroxide; dimethyl sulfate; und anschliessend mit CH₃I in Methanol;

DOI:10.1021/ja01636a046

upstream raw materials:

1,2-bis-(p-methylphenylsulfonamido)-benzene

1-dimethylamino-1-methoxyethylene

dimethyl sulfate

methyl iodide

Downstream raw materials:

N,N'-dimethyl-1,2-phenylenediamine

1,3-dimethyl-2-phenyl-2,3-dihydro-1H-benzo[d]imidazole

1,3-dimethyl-2-(o-hydroxyphenyl)-2,3-dihydro-1H-benzo[d]imidazole

1,3-dimethyl-2-(3-nitro-phenyl)-2,3-dihydro-1H-benzoimidazole