N,N-dimethylbenzene-1,2-diamine

Base Information

• Chemical Name: N,N-dimethylbenzene-1,2-diamine
• CAS No.: 3213-79-4
• Molecular Formula: C8H12N2
• Molecular Weight: 136.197
• Hs Code.: 2921590090
• Mol file: 3213-79-4.mol

Synonyms:N,N'-Dimethyl-1,2-phenylenediamine;N,N inverted exclamation marka-Dimethyl-1,2-phenylenediamine;1,2-Benzenediamine, N,N‘-dimethyl-;N,N'-Dimethyl-1,2-diaminobenzene;o-N,N'-dimethylphenylenediamine;N,N'-dimethyl-o-phenylenediamine;1,2-Benzenediamine,N,N'-dimethyl;N,N inverted exclamation marka-Dimethyl-1,2-diaminobenzene;

Chemical Property of N,N-dimethylbenzene-1,2-diamine

Chemical Property:

• Melting Point: 34.5°C
• Refractive Index: n20/D1.592
• Boiling Point: 240.49°C (rough estimate)
• PKA: 8.30±0.10(Predicted)
• Flash Point: >110℃
• PSA: 24.06000
• Density: 1.262 g/mL at 25 °C
• LogP: 1.91600
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C

Purity/Quality:

98%,99%, ^*data from raw suppliers

N1,N2-Dimethylbenzene-1,2-diamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N,N-dimethylbenzene-1,2-diamine

There total 31 articles about N,N-dimethylbenzene-1,2-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

N,N’-dimethyl-N,N’-di(p-toluenesulfonyl)-o-phenylenediamine (29627-62-1) → N,N'-dimethyl-1,2-phenylenediamine (3213-79-4)

Guidance literature:

With sulfuric acid; In water; at 100 ℃; for 8h;

DOI:10.1002/anie.201207410

Reference yield: 85.0%

methyl magnesium iodide (917-64-6) + C26H36N4(2+)*2I(1-) → 2,11-dodecadione (7029-09-6) + N,N'-dimethyl-1,2-phenylenediamine (3213-79-4)

Guidance literature:

methyl magnesium iodide; C₂₆H₃₆N₄⁽²⁺⁾*2I^(1-); In tetrahydrofuran; at 20 ℃; for 30h;

With hydrogenchloride; In tetrahydrofuran; water; Heating;

DOI:10.1081/SCC-200028613

Reference yield: 83.0%

methyl magnesium iodide (917-64-6) + C24H32N4(2+)*2I(1-) → decane-2,9-dione (16538-91-3) + N,N'-dimethyl-1,2-phenylenediamine (3213-79-4)

Guidance literature:

methyl magnesium iodide; C₂₄H₃₂N₄⁽²⁺⁾*2I^(1-); In tetrahydrofuran; at 20 ℃; for 30h;

With hydrogenchloride; In tetrahydrofuran; water; Heating;

DOI:10.1081/SCC-200028613

upstream raw materials:

methanol

N,N'-(o-phenylene)di(acetamide)

1,3-bis-chloromethyl-1,3-dihydro-benzoimidazol-2-one

N,N’-dimethyl-N,N’-di(p-toluenesulfonyl)-o-phenylenediamine

Downstream raw materials:

1,2-bis(N-benzoyl-N-methylamino)benzene

1,3-Dimethyl-2-phenyl-2,3-dihydro-1H-1,3,2-benzodiaza-phosphol-2-sulfid

1,3-dimethyl-2-phenyl-2,3-dihydro-1H-benzo[1,3,2]diazaphosphole

2-(4-methylphenyl)-1,3-dimethyl-benzimidazoline

Refernces

• 1、 -. "BORYLIMIDE CATALYSTS". Paragraph 0081. . Retrieved 2020/06/10.
• 2、 Lator, Alexis,Gaillard, Sylvain,Poater, Albert,Renaud, Jean-Luc. "Well-Defined Phosphine-Free Iron-Catalyzed N-Ethylation and N-Methylation of Amines with Ethanol and Methanol". supporting information. p. 5985 - 5990. Retrieved 2018/10/02.