1H-Indole-3-ethanol, 5-chloro-1-(diphenylmethyl)-2-phenyl-

Base Information

Chemical Name:1H-Indole-3-ethanol, 5-chloro-1-(diphenylmethyl)-2-phenyl-
CAS No.:872674-53-8
Molecular Formula:C29H24ClNO
Molecular Weight:437.969
Hs Code.:
DSSTox Substance ID:DTXSID50469663

Synonyms:872674-53-8;1H-Indole-3-ethanol, 5-chloro-1-(diphenylmethyl)-2-phenyl-;DTXSID50469663

Suppliers and Price of 1H-Indole-3-ethanol, 5-chloro-1-(diphenylmethyl)-2-phenyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 1H-Indole-3-ethanol, 5-chloro-1-(diphenylmethyl)-2-phenyl-

Chemical Property:

XLogP3:7.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:6
Exact Mass:437.1546421
Heavy Atom Count:32
Complexity:548

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=C(C3=C(N2C(C4=CC=CC=C4)C5=CC=CC=C5)C=CC(=C3)Cl)CCO

Technology Process of 1H-Indole-3-ethanol, 5-chloro-1-(diphenylmethyl)-2-phenyl-

There total 6 articles about 1H-Indole-3-ethanol, 5-chloro-1-(diphenylmethyl)-2-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 872674-51-6
2-(5-chloro-2-phenyl-1H-indol-3-yl)ethanol

: 776-74-9
Bromodiphenylmethane

: 872674-53-8
2-[5-chloro-1-(diphenylmethyl)-2-phenyl-1H-indol-3-yl]ethanol

Guidance literature:: 2-(5-chloro-2-phenyl-1H-indol-3-yl)ethanol; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 0.5h;

Bromodiphenylmethane; In N,N-dimethyl-formamide; at 0 - 20 ℃;
DOI:10.1021/jm0507882

Reference yield:

: 872674-50-5
methyl (5-chloro-2-phenyl-1H-indol-3-yl)oxoacetate

: 872674-53-8
2-[5-chloro-1-(diphenylmethyl)-2-phenyl-1H-indol-3-yl]ethanol

Guidance literature:: Multi-step reaction with 2 steps

1.1: LiAlH₄ / tetrahydrofuran / 0.5 h / 10 °C

2.1: NaH / dimethylformamide / 0.5 h / 0 °C

2.2: 40 percent / dimethylformamide / 0 - 20 °C

With lithium aluminium tetrahydride; sodium hydride; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1021/jm0507882

Reference yield:

: 23746-76-1
5-chloro-2-phenylindole

: 872674-53-8
2-[5-chloro-1-(diphenylmethyl)-2-phenyl-1H-indol-3-yl]ethanol

Guidance literature:: Multi-step reaction with 3 steps

1.1: diethyl ether / 0.5 h / cooling

1.2: NEt₃ / diethyl ether

2.1: LiAlH₄ / tetrahydrofuran / 0.5 h / 10 °C

3.1: NaH / dimethylformamide / 0.5 h / 0 °C

3.2: 40 percent / dimethylformamide / 0 - 20 °C

With lithium aluminium tetrahydride; sodium hydride; In tetrahydrofuran; diethyl ether; N,N-dimethyl-formamide;
DOI:10.1021/jm0507882