7-bromo-5-phenyl-1,2-dihydro-2H-1,4-benzodiazepin-2-one

Base Information

Chemical Name:7-bromo-5-phenyl-1,2-dihydro-2H-1,4-benzodiazepin-2-one
CAS No.:2894-61-3
Molecular Formula:C15H11 Br N2 O
Molecular Weight:315.169
Hs Code.:2933990090
Mol file:2894-61-3.mol

Synonyms:7-Bromo-5-phenyl-1,3-dihydrobenzo[e]-1,4-diazepin-2-one;7-Bromo-5-phenyl-1H-benzo[e][1,4]diazepin-2(3H)-one;7-Bromo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one; BD 3; BD 3(tranquilizer); Desalkylgidazepam

Suppliers and Price of 7-bromo-5-phenyl-1,2-dihydro-2H-1,4-benzodiazepin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
7-Bromo-5-phenyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one 95%+
5g
$ 1831.00

Matrix Scientific
7-Bromo-5-phenyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one 95%+
2.500g
$ 1212.00

Matrix Scientific
7-Bromo-5-phenyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one 95%+
1g
$ 555.00

American Custom Chemicals Corporation
7-BROMO-5-PHENYL-1,3-DIHYDRO-BENZO[E][1,4]DIAZEPIN-2-ONE 95.00%
5MG
$ 498.99

AK Scientific
7-Bromo-5-phenyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one
1g
$ 580.00

AK Scientific
7-Bromo-5-phenyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one
250mg
$ 283.00

Total 50 raw suppliers

Chemical Property of 7-bromo-5-phenyl-1,2-dihydro-2H-1,4-benzodiazepin-2-one

Chemical Property:

Vapor Pressure:8.13E-09mmHg at 25°C
Melting Point:220-221 °C(Solv: ethyl ether (60-29-7))
Boiling Point:464.8°Cat760mmHg
PKA:11.72±0.70(Predicted)
Flash Point:234.9°C
PSA：44.95000
Density:1.51g/cm³
LogP:2.75930

Purity/Quality:

99%, ^*data from raw suppliers

7-Bromo-5-phenyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one 95%+ ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Description Bromonordiazepam is the active metabolite of of the Soviet developed Gidazepam. Bromonordiazepam is closely related is to Diazepam in structure, has a very long half life and is exceptionally anxiolytic with limited non-therapeutic potential.
Uses 7-Bromo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one inhibits HIV-1 reverse transcription.

Technology Process of 7-bromo-5-phenyl-1,2-dihydro-2H-1,4-benzodiazepin-2-one

There total 12 articles about 7-bromo-5-phenyl-1,2-dihydro-2H-1,4-benzodiazepin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one

: 2894-61-3
7-bromo-5-phenyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one

Guidance literature:: With sulfuric acid; bromine; In acetic acid; at 20 ℃; for 48h;

Reference yield: 88.0%

: 39859-36-4
2-amino-5-bromobenzophenone

: 79-04-9
chloroacetyl chloride

: 2894-61-3
7-bromo-5-phenyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one

Guidance literature:: 2-amino-5-bromobenzophenone; chloroacetyl chloride; With potassium carbonate; In tetrahydrofuran; at 0 ℃; for 0.5h;

With ammonium hydroxide; potassium carbonate; In tetrahydrofuran; at 20 ℃; for 15h; Further stages.;
DOI:10.1080/00397910701750078