N-methylmalonamic acid

Base Information

• Chemical Name: N-methylmalonamic acid
• CAS No.: 42105-98-6
• Molecular Formula: C₄H₇NO₃
• Molecular Weight: 117.104
• Hs Code.: 2924199090
• Mol file: 42105-98-6.mol

Synonyms:N-Methylmalonamicacid

Chemical Property of N-methylmalonamic acid

Chemical Property:

• Vapor Pressure: 1.81E-07mmHg at 25°C
• Boiling Point: 398.6°Cat760mmHg
• Flash Point: 194.9°C
• PSA: 66.40000
• Density: 1.231g/cm³
• LogP: -0.40200

Purity/Quality:

97% ^*data from raw suppliers

3-(methylamino)-3-oxopropanoicacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-methylmalonamic acid

There total 3 articles about N-methylmalonamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

cycl-isopropylidene malonate (2033-24-1) + methylamine (74-89-5) → 3-(methylamino)-3-oxopropanoic acid (42105-98-6)

Guidance literature:

In water; for 52h;

DOI:10.1021/ja00004a016

Reference yield:

S-phenyl hydrogen thiomalonate (4279-77-0) + methylamine (74-89-5) → 3-(methylamino)-3-oxopropanoic acid (42105-98-6)

Guidance literature:

With ethylenediaminetetraacetic acid; potassium chloride; water; In acetonitrile; at 25 ℃; Rate constant; Mechanism;

Reference yield:

→ 3-(methylamino)-3-oxopropanoic acid (42105-98-6)

Guidance literature:

2,2-Difluoro-1-methyl-4-oxo-3-(trifluormethyl)-3-azetidin-carbonylfluorid (IV, R=CH3), cc. H2SO4 (S.102);

DOI:10.1016/S0022-1139(00)82863-8

upstream raw materials:

cycl-isopropylidene malonate

methylamine

S-phenyl hydrogen thiomalonate

Downstream raw materials:

methyl 3-(methylamino)-3-oxopropanoate