7-Methoxy-5H-[1]benzopyrano[3,4-c]pyridin-5-one

Base Information

Chemical Name:7-Methoxy-5H-[1]benzopyrano[3,4-c]pyridin-5-one
CAS No.:87308-11-0
Molecular Formula:C13H9NO3
Molecular Weight:227.219
Hs Code.:
DSSTox Substance ID:DTXSID10519133
Wikidata:Q82382107

Synonyms:87308-11-0;7-METHOXY-5H-CHROMENO[3,4-C]PYRIDIN-5-ONE;7-Methoxy-5H-[1]benzopyrano[3,4-c]pyridin-5-one;DTXSID10519133

Suppliers and Price of 7-Methoxy-5H-[1]benzopyrano[3,4-c]pyridin-5-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 7-Methoxy-5H-[1]benzopyrano[3,4-c]pyridin-5-one

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:227.058243149
Heavy Atom Count:17
Complexity:307

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=CC2=C1OC(=O)C3=C2C=CN=C3

Technology Process of 7-Methoxy-5H-[1]benzopyrano[3,4-c]pyridin-5-one

There total 2 articles about 7-Methoxy-5H-[1]benzopyrano[3,4-c]pyridin-5-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 27.0%

: 87902-86-1
3-(4,4-Dimethyl-2-oxazolinyl)-4-(2,3-dimethoxyphenyl)pyridine

: 87902-91-8
3-(4,4-dimethyloxazolin-2-yl)-4-(2-methoxy-3-hydroxyphenyl)pyridine

: 87308-11-0
7-methoxy<1>benzopyrano<3,4-c>pyridin-5(2H)-one

Guidance literature:: With methanesulfonic acid; DL-methionine; at 85 ℃; for 90h;
DOI:10.1021/jo00175a011

Reference yield:

: 79-37-8
oxalyl dichloride

: 87307-79-7
3-methoxy-2-(phenylmethoxy)-α-methylstyrene

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 87307-82-2
4-<3-methoxy-2-(phenylmethoxy)phenyl>pyridine-3-carboxaldehyde

: 87308-11-0
7-methoxy<1>benzopyrano<3,4-c>pyridin-5(2H)-one

Guidance literature:: With ammonium acetate; Yield given. Multistep reaction. Yields of byproduct given; 1.) 1,2-dichloroethane, reflux, 3 h, 2.) HAc, H₂O, 100 deg C, 1 h;
DOI:10.1021/jo00172a032

Reference yield:

: 87308-11-0
7-methoxy<1>benzopyrano<3,4-c>pyridin-5(2H)-one

: 87307-84-4
ethyl 3-<4-(2-hydroxy-3-methoxyphenyl)pyridin-3-yl>propanoate

Guidance literature:: Multi-step reaction with 6 steps

1: dimethylformamide / 1 h / -65 °C

2: dimethylformamide / 1.) from -65 deg C to RT, 3 h, 2.) RT, 2 h

3: 82 percent / DIBALH / toluene / 3 h / -78 - 0 °C

4: 92 percent / MnO₂ / CH₂Cl₂ / 14 h / Heating

5: 91 percent / pyridine, piperidine / Heating

6: 92 percent / H₂ / 5percent Pd/C / ethanol

With piperidine; pyridine; manganese(IV) oxide; hydrogen; diisobutylaluminium hydride; palladium on activated charcoal; In ethanol; dichloromethane; N,N-dimethyl-formamide; toluene;
DOI:10.1021/jm00045a017