Dimethyl 2-chloro-5-nitrobenzene-1,3-dicarboxylate

Base Information

Chemical Name:Dimethyl 2-chloro-5-nitrobenzene-1,3-dicarboxylate
CAS No.:87350-69-4
Molecular Formula:C₁₀H₈ClNO₆
Molecular Weight:273.63
Hs Code.:
DSSTox Substance ID:DTXSID40527307
Wikidata:Q82396486

Synonyms:Dimethyl 2-chloro-5-nitrobenzene-1,3-dicarboxylate;87350-69-4;1,3-DIMETHYL 2-CHLORO-5-NITROBENZENE-1,3-DICARBOXYLATE;DTXSID40527307;AKOS001877501

Suppliers and Price of Dimethyl 2-chloro-5-nitrobenzene-1,3-dicarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of Dimethyl 2-chloro-5-nitrobenzene-1,3-dicarboxylate

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:273.0040147
Heavy Atom Count:18
Complexity:329

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC(=O)C1=CC(=CC(=C1Cl)C(=O)OC)[N+](=O)[O-]

Technology Process of Dimethyl 2-chloro-5-nitrobenzene-1,3-dicarboxylate

There total 2 articles about Dimethyl 2-chloro-5-nitrobenzene-1,3-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 67-56-1
methanol

: 87350-83-2
2-Chloro-5-nitro-1,3-benzenedicarboxylic acid

: 87350-69-4
Dimethyl 2-chloro-5-nitro-1,3-benzenedicarboxylate

Guidance literature:: With hydrogenchloride; for 2h; Heating;
DOI:10.1021/jo00172a040

Reference yield:

: 13049-16-6
2,6-dicarboxychlorobenzene

: 87350-69-4
Dimethyl 2-chloro-5-nitro-1,3-benzenedicarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 86 percent / fuming nitric acid, 45percent oleum / 6 h / Heating

2: 88 percent / hydrogen chloride / 2 h / Heating

With hydrogenchloride; sulfuric acid; nitric acid;
DOI:10.1021/jo00172a040