Hydantoin, 3-benzyloxy-

Base Information

• Chemical Name: Hydantoin, 3-benzyloxy-
• CAS No.: 30204-23-0
• Molecular Formula: C10H10 N2 O3
• Molecular Weight: 206.201
• DSSTox Substance ID: DTXSID90184303
• Nikkaji Number: J77.698J
• Wikidata: Q83055222
• Mol file: 30204-23-0.mol

Synonyms:3-Benzyloxy-hydantoin;HYDANTOIN, 3-BENZYLOXY-;30204-23-0;3-(benzyloxy)imidazolidine-2,4-dione;BRN 0791238;3-Benzyloxyhydantoin;SCHEMBL15264534;DTXSID90184303;YBCXJEMZAPOJOV-UHFFFAOYSA-N;LS-75987

Chemical Property of Hydantoin, 3-benzyloxy-

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: 1.35g/cm³
• XLogP3: 0.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 206.06914219
• Heavy Atom Count: 15
• Complexity: 261

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1C(=O)N(C(=O)N1)OCC2=CC=CC=C2

Technology Process of Hydantoin, 3-benzyloxy-

There total 4 articles about Hydantoin, 3-benzyloxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 20.0%

glycine ethyl ester hydrochloride (5680-79-5,883886-67-7) + 1-(4-nitrophenol)-N-(O-benzylhydroxy) carbamate (83948-52-1) → 3-(benzyloxy)imidazolidine-2,4-dione (30204-23-0)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 12h;

DOI:10.2174/1573406411666150708111631

Reference yield:

O-benzylglycine hydroxamic acid (16975-23-8) + 1,1'-carbonyldiimidazole (530-62-1) → 3-(benzyloxy)imidazolidine-2,4-dione (30204-23-0)

Guidance literature:

With 4-methyl-morpholine; In dichloromethane; at 20 ℃;

Reference yield:

(benzyloxycarbamoylmethyl)carbamic acid tert-butyl ester (63648-89-5) → 3-(benzyloxy)imidazolidine-2,4-dione (30204-23-0)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrogenchloride / 1,4-dioxane / 1 h / 20 °C

2: 4-methyl-morpholine / dichloromethane / 20 °C

With 4-methyl-morpholine; hydrogenchloride; In 1,4-dioxane; dichloromethane;

upstream raw materials:

(benzyloxycarbamoylmethyl)carbamic acid tert-butyl ester

O-benzylglycine hydroxamic acid

1,1'-carbonyldiimidazole

O-benzylhydoxylamine hydrochloride

Downstream raw materials:

3-hydroxyimidazolidine-2,4-dione