2-(4-Biphenylyl)-2-methyloxirane

Base Information

• Chemical Name: 2-(4-Biphenylyl)-2-methyloxirane
• CAS No.: 64371-62-6
• Molecular Formula: C15H14 O
• Molecular Weight: 210.2711
• UNII: 01ZVJ3F1PM
• DSSTox Substance ID: DTXSID70982925
• Wikidata: Q27231467
• Mol file: 64371-62-6.mol

Synonyms:2-(4-Biphenylyl)-2-methyloxirane;64371-62-6;01ZVJ3F1PM;2-((1,1'-Biphenyl)-4-yl)-2-methyloxirane;2-([1,1'-BIPHENYL]-4-YL)-2-METHYLOXIRANE;CCRIS 2736;2-methyl-2-(4-phenylphenyl)oxirane;UNII-01ZVJ3F1PM;2-(1,1'-Biphenyl)-4-yl-2-methyloxirane;Oxirane, 2-(1,1'-biphenyl)-4-yl-2-methyl-;DTXSID70982925;AKOS012067848;EN300-1870326;Q27231467

Chemical Property of 2-(4-Biphenylyl)-2-methyloxirane

Chemical Property:

• Vapor Pressure: 0.000332mmHg at 25°C
• Boiling Point: 329.8°Cat760mmHg
• Flash Point: 148.1°C
• Density: 1.094g/cm³
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 210.104465066
• Heavy Atom Count: 16
• Complexity: 236

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1(CO1)C2=CC=C(C=C2)C3=CC=CC=C3

Technology Process of 2-(4-Biphenylyl)-2-methyloxirane

There total 4 articles about 2-(4-Biphenylyl)-2-methyloxirane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

biphenyl-4-acetaldehyde (92-91-1) + trimethylsulfoxonium iodide (1774-47-6) → 2-(1,1'-biphenyl-4-yl)-2-methyloxirane (64371-62-6)

Guidance literature:

With potassium tert-butylate; In dimethyl sulfoxide; at 20 ℃; for 2h;

DOI:10.1002/ejoc.200600654

Reference yield: 65.0%

1-bromo-2-(4-biphenylyl)propan-2-ol (182816-12-2) → 2-(1,1'-biphenyl-4-yl)-2-methyloxirane (64371-62-6)

Guidance literature:

With potassium hydroxide; In methanol; for 0.5h; Heating;

DOI:10.1016/0040-4020(96)00758-2

Reference yield:

2-([1,1′-biphenyl]-4-yl)oxirane (36099-26-0) + methyl iodide (74-88-4) → 2-(1,1'-biphenyl-4-yl)-2-methyloxirane (64371-62-6)

Guidance literature:

2-([1,1′-biphenyl]-4-yl)oxirane; With sec.-butyllithium; In tetrahydrofuran; hexane; cyclohexane; at -78 ℃; for 0.00661111h; flow microreactor;

methyl iodide; In tetrahydrofuran; hexane; cyclohexane; at -78 ℃; for 0.000555556h; flow microreactor;

DOI:10.1002/chem.201000815

upstream raw materials:

1-bromo-2-(4-biphenylyl)propan-2-ol

biphenyl-4-acetaldehyde

trimethylsulfoxonium iodide

4-(propen-2-yl)biphenyl